51626-34-7Relevant academic research and scientific papers
A convenient synthesis, reactions and biological studies of some novel selenolo[2,3-c]pyrazole compounds as antimicrobial and anti-inflammatory agents
Zaki, Remon M.,El-Ossaily, Yasser A.,Geies, Ahmed A.
, p. 893 - 908 (2016/04/20)
5-Chloro-3-methyl-1-phenylpyrazole-4-carbonitrile 3 was reacted with selenium in the presence of sodium borohydride and chloroacetamide to afford selanyl acetamide 5, which underwent Thorpe-Ziegler cyclization upon heating with sodium ethoxide to give the
A convenient synthesis and biological activity of novel thieno[2,3-c]pyrazole compounds as antimicrobial and anti-inflammatory agents
El-Dean, Adel M. Kamal,Zaki, Remon M.,Abdulrazzaq, Abdullah Y.
, p. 97 - 104 (2015/02/05)
A new method for synthesizing 4-amino-3-methyl-1-phenyl-1H-5-substituted thieno[2,3-c]pyrazole was reported. The substituted groups at position 5 include carbonitrile, carboxamide, N-phenyl carboxamide, and benzoyl groups. The newly synthesized compounds
Thieno[2,3-c]pyrazoles and related heterocycles
Haider, Norbert,Farghaly, Abdel-Rahman,Al-Mekhlafi, Nabil,El-Kashef, Hussein
, p. 761 - 765 (2007/10/03)
5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde (1) was converted, via the oxime 2, into the chloronitrile 3. Treatment of compound 3 with methyl thioglycolate gave the novel methyl 4-amino-3-methyl-1-phenyl-1H-thieno [2,3-c]pyrazole-5-carboxylate
GROUP DIPOLE MOMENTS OF SUBSTITUENTS AT POSITIONS 4 AND 5 OF NITROGEN-CONTAINING FIVE-MEMBERED HETEROCYCLES
Fradkina, S. P.,Kvitko, I. Ya.,Alam, L. V.,Fedorova, N. S.
, p. 191 - 196 (2007/10/02)
The dipole moments of the 5-chloro-4-cyano derivatives of oxazole, thiazole, imidazole, and pyrazole were determined.The group dipole moments of substituents at positions 2 and 3 of furan, thiophene, and pyrrole can be used for vector calculation of the dipole moments of various 4- and 5-substituted azoles.
