51627-99-7

Basic information

• Product Name: ethyl 2-(4-bromophenyl)acetimidate hydrochloride
• Synonyms: ethyl 2-(4-bromophenyl)acetimidate hydrochloride
• CAS NO: 51627-99-7
• Molecular Weight: 278.576
• Mol File: 51627-99-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-bromophenyl)acetimidate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-bromophenyl)acetimidate hydrochloride(51627-99-7)
• EPA Substance Registry System: ethyl 2-(4-bromophenyl)acetimidate hydrochloride(51627-99-7)

Safety Data

• Hazardous Substances Data: 51627-99-7(Hazardous Substances Data)

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 64-17-5 ethanol 

Downstream Products

• 1450838-42-2 phenyl[2-(4-bromobenzyl)-1H-1,3-benzimidazol-5-yl]methanone 
• 69374-79-4 2-(4-bromophenyl)-2-oxoacetamide 
• 100622-41-1 2-(4-bromobenzyl)-1H-benzo[d]imidazole 

Relevant articles and documents

Copper(II)-Mediated Aerobic Oxidation of Benzylimidates: Synthesis of Primary α-Ketoamides

A simple and straightforward method for the synthesis of primary α-ketoamides has been discovered. The reaction represents the first example of benzylimidates directly converting to primary α-ketoamides by using sustainable molecular oxygen as an oxidant. This reaction proceeds in the presence of copper(II) salt via cleavage of benzylic C-H and C-O bonds of the benzylimidates with liberation of alcohols as the only byproduct. A wide substrate scope, operationally mild conditions, the use of single substrates, and a reaction scaled up to grams make this strategy very attractive and practical. Furthermore, mechanistic studies illustrate that the imidate group adjacent to the benzylic position plays crucial role in facilitating this chemical process.

Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents

A library of eighty-six assorted benzimidazole derivatives was screened for antiviral activity against a panel of ten RNA and DNA viruses. Fifty-two of them displayed different levels of activity against one or more viruses, among which CVB-5, RSV, BVDV a

Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives

This study presents a synthesis of new series of some benzimidazole, bisbenzimidazole and perimidine derivatives via microwave technique, which, leads to the good product yields and short reaction times. The structure of newly synthesized compounds was confirmed by 1H NMR and 13C NMR spectra. These compounds were screened for their lipase inhibition activity. Then, all compounds were evaluated with regard to pancreatic lipase activity, and some of the 2-substituted perimidines, bisperimidine and bisbenzimidazole derivatives showed lipase inhibition at various concentrations.