51638-91-6

Basic information

• Product Name: (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
• Synonyms: (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
• CAS NO: 51638-91-6
• Molecular Weight: 406.435
• Mol File: 51638-91-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate(51638-91-6)
• EPA Substance Registry System: (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate(51638-91-6)

Safety Data

• Hazardous Substances Data: 51638-91-6(Hazardous Substances Data)

Usage

General Description

The chemical compound "(3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate" is a complex organic molecule with multiple functional groups. The compound consists of a benzoate group, which is a common feature in numerous pharmaceutical drugs and often contributes both to their biological activity and their metabolism in the human body. Present too is a hexahydro-2H-cyclopenta[b]furan ring - a type of cyclic oxygenated structure that's common in naturally occurring organic compounds. This is attached to an oxo-butene tail with a phenoxy group (a benzene ring attached via an oxygen atom). Such phenoxy groups are common in certain pesticides and are also known to be metabolised by the body. (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate's structure hints at potential bioactive properties, but without specific context or research, it's impossible to infer its exact purpose or effect.

Upstream product

• 40665-68-7 dimethyl (3-phenoxy-2-oxopropyl)phosphonate 
• 39746-01-5 (1S,5R,6R,7R)-6-formyl-7-benzoyloxy-2-oxabicyclo[3.3.0]octan-3-one 

Downstream Products

• 1449413-13-1 C₂₂H₂₈F₂O₅*C₁₂H₂₃N 
• 51705-18-1 [3aR,4R(1E,3S),5R,6aS]-5-benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one 
• 59618-87-0 [3aR,4R(1E),5R,6aS]-5-(benzoyloxy)-4-[4-phenoxy-3,3-(ethylenedioxy)butenyl]-hexahydro-2H-cyclopenta[b]furan-2-one 
• 209860-87-7 tafluprost 
• 209860-88-8 AFP-172 
• 209861-02-9 (3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2,5-diol 
• 209861-01-8 (3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-5-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one 
• 208112-11-2 (5Z)-(9S,11R,15R)-9-hydroxy-15-fluoro-16-phenoxy-11-(tetrahydropyran-2-yloxy)-17,18,19,20-tetranor-5-prostenoic acid isopropyl ester 
• 242464-10-4 (5Z,13E)-(9S,11R,15RS)-15-fluoro-9-hydroxy-16-phenoxy-11-(tetrahydropyran-2-yloxy)-17,18,19,20-tetranor-5,13-prostadienoic acid isopropyl ester 
• 242464-07-9 (Z)-7-[(1R,2R,3R,5S)-2-((E)-3-Fluoro-4-phenoxy-but-1-enyl)-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid 

Relevant articles and documents

Identification and efficient synthetic method for preparation of cyclopentane-1,3-diol impurity in tafluprost drug

In present work, the isolation, synthesis and characterization of the identified triol impurity present in tafluprost is described. This investigation helps to avoid formation of impurity by control the reaction and its leads to improving high yields of t

AMINE SALTS OF PROSTAGLANDIN ANALOGS

The present application relates to amine salts of prostaglandin analogs and their uses for the preparation of substantially pure prostaglandin analogs. Specific embodiments relate to amine salts of tafluprost and their uses for the preparation of substant

Synthesis of the highly potent prostanoid FP receptor agonist, AFP-168: A novel 15-deoxy-15,15-difluoroprostaglandin F2α derivative

A novel 15-deoxy-15,15-difluoro-prostaglandin(PG)F2α derivative 6 (AFP-168) has been synthesized from the Corey aldehyde in six steps. A key aspect of this route is difluorination of an enone and a stereoselective Wittig reaction. The compound shows high affinity to the FP receptor and potent activities for an anti-glaucoma agent.