51646-33-4

Upstream product

• 141-97-9 ethyl acetoacetate 
• 3922-47-2 3-(benzylthio)-1H-1,2,4-triazol-5-amine 

Downstream Products

• 51646-37-8 2,2'-(2-benzylsulfanyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylazanediyl)-bis-ethanol 
• 51646-39-0 2-benzylsulfanyl-5-methyl-7-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 51646-38-9 2-benzylsulfanyl-5-methyl-7-piperidin-1-yl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 51646-35-6 (2-benzylsulfanyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-diethyl-amine 
• 51646-41-4 2-benzylsulfanyl-8-(N',N'-dimethyl-hydrazino)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 51646-36-7 (2-benzylsulfanyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-dimethyl-amine 
• 80726-65-4 (2-Benzylsulfanyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-propyl-amine; hydrochloride 
• 51646-42-5 2-benzylsulfanyl-5-methyl-4H-[1,2,4]triazolo[1,5-a]pyrimidine-7-thione 
• 51646-34-5 2-(benzylthio)-7-chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine 

Relevant academic research and scientific papers

2-(Alkylthio)-1,2,4-triazolo[1,5-a]pyrimidines as adenosine cyclic 3',5'-monophosphate phosphodiesterase inhibitors with potential as new cardiovascular agents

A series of new 2-(alkylthio)-5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines have been prepared as inhibitors of cAMP phosphodiesterase from various tissues. These derivatives were prepared via ring closure of various requisite 3-amino-1,2,4-triazole

2-SUBSTITUTED-S-TRIAZOLO[1,5A]-PYRIMIDINES

2-Substituted-s-triazolo[1,5a]pyrimidines are disclosed which are useful as inhibitors of phosphodiesterase enzymes or intermediates in the production process. Such comoounds are of the following structure: wherein X, R, R1, R2 and R3 are as defined herei