516462-74-1

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 111-42-2 2,2'-iminobis[ethanol] 
• 70782-12-6 N-benzyloxycarbonyldiethanolamine 
• 241489-71-4 {2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-(2-hydroxy-ethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester 

Downstream Products

• 745795-96-4 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Lys}-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745796-01-4 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Orn}-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745796-06-9 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Dab}-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745795-97-5 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Lys}-O-(4,4'-dimethoxytrityl)diethanolamine 
• 745795-93-1 N-(N^α,N^ε-bis-Fmoc-L-Lys)-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745795-99-7 N-(N^α,N^ε-bis-Fmoc-L-Orn)-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745796-02-5 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Orn}-O-(4,4'-dimethoxytrityl)diethanolamine 
• 745796-07-0 N-{N^α,N^ε-bis(pyrene-1-carbonyl)-L-Dab}-O-(4,4'-dimethoxytrityl)diethanolamine 
• 745796-04-7 N-(N^α,N^ε-bis-Fmoc-L-Dab)-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745795-95-3 N-L-Lys-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745796-00-3 N-L-Orn-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 
• 745796-05-8 N-L-Dab-O-(4,4'-dimethoxytrityl)-O'-(tert-butyldimethylsilyl)diethanolamine 

Relevant academic research and scientific papers

Modified oligonucleotides and compound that can be used for synthesizing same

The present disclosure falls within the field of biomedical technology, and in particular relates to modified oligonucleatides and a compound that can be used for synthesizing same and a method for modifying oligonucleotides. The present disclosure also relates to the use of the modified oligonucleotides for preventing and/or treating diseases associated with the liver in a subject.

Pyrene-labeled oligodeoxynucleotide probe for detecting base insertion by excimer fluorescence emission

Novel ODN probes for insertion polymorphism detection have been devised. The ODN probes labeled with two pyrene chromophores emit strong excimer fluorescence when hybridized with DNA containing one inserted base. This method is useful for the determinatio

Synthesis of triple helix forming oligonucleotides with a phenanthroline moiety into the 3′-3′ inversion site of polarity

A protocol for the synthesis of triplex forming oligonucleotides containing a chelating molecule in the 3′-3′ inversion site of polarity is reported. A number of 16-mers have been synthesized and UV spectroscopy employed to evaluate the stability of their triple helix complexes with the pertinent double-strand oligonucleotide targets. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2002.