51671-69-3

Basic information

• Product Name: Benzoyl chloride, 2-methoxy-4-methyl- (9CI)
• Synonyms: Benzoyl chloride, 2-methoxy-4-methyl- (9CI);2-methoxy-4-methylbenzoyl chloride
• CAS NO: 51671-69-3
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.61956
• Product Categories: ACIDHALIDE
• Mol File: 51671-69-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 282.7±20.0 °C(Predicted)
• Appearance: /
• Density: 1.182±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoyl chloride, 2-methoxy-4-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-methoxy-4-methyl- (9CI)(51671-69-3)
• EPA Substance Registry System: Benzoyl chloride, 2-methoxy-4-methyl- (9CI)(51671-69-3)

Safety Data

• Hazardous Substances Data: 51671-69-3(Hazardous Substances Data)

Upstream product

• 81245-24-1 methyl 4-methyl-2-methoxybenzoate 
• 50-85-1 2-hydroxy-p-toluic acid 
• 1706-11-2 2,5-Dimethyl-anisol 
• 111210-20-9 N,N-diethyl-2-methoxy-4-methylbenzamide 
• 704-45-0 2-methoxy-4-methylbenzoic acid 

Downstream Products

• 36871-54-2 1-(2-methoxy-4-methyl-phenyl)-propan-1-one 
• 1215860-21-1 C₂₇H₃₂N₄O₃Si 
• 1452584-44-9 C₁₈H₁₉NO₂ 
• 102349-40-6 2-Formyl-6-methoxy-4-methyl-benzoic acid methyl ester 
• 1353486-44-8 tert-butyl 2-methoxy-4-methylbenzoate 

Relevant articles and documents

Total Synthesis of (+)-Rubellin C

The rubellins are a family of stereochemically complex anthraquinoid heterodimers containing an unprecedented chemical scaffold. Although the rubellins have been known for over three decades, no total synthesis has been achieved since their discovery. The

Design, synthesis, and preliminary biological evaluation of 3′,4′,5′-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents

According to the pharmacophore combination principle, a set of new 3′,4′,5′-trimethoxy flavonoid salicylate derivatives were designed, synthesized, and evaluated for biological activity. The cytotoxicity evaluation revealed that compound 10v exhibited higher potency than 5-Fu against HCT-116 cells. Preliminary biological activity studies showed that compound 10v could inhibit the colony formation and migration of HCT-116 cells. Besides, the Hoechst 33258 staining assay and flow cytometry revealed that treatment with compound 10v induced the apoptosis of HCT-116 cells in a concentration-dependent manner, while it had no effect on their cell cycle. The WB analysis suggested that HIF-1α, tubulin, HK-2, and PFK might be the potential pharmacophore targets of compound 10v. Tubulin was a potential drug target for compound 10v, which was explained by analyzing the crystal structure of compound 10v complexed with tubulin. These results indicated that compound 10v might be a promising anti-tumor agent candidate, deserving further optimization and evaluation.

Total Synthesis of Asperphenins A and B

The first total synthesis of asperphenins A and B has been accomplished in a concise, highly stereoselective fashion from commercially available materials (15 steps, 9.7% and 14.2% overall yields, respectively). The convergent route featured the judicious