57415-35-7

Basic information

• Product Name: 2-methoxy-4-methyl-benzaldehyde
• Synonyms: 2-methoxy-4-methyl-benzaldehyde;4-Methyl-6-methoxybenzaldehyde;2-methoxy-4-methylbenzaldehyde(SALTDATA: FREE)
• CAS NO: 57415-35-7
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.17
• Mol File: 57415-35-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 40-43 ºC
• Boiling Point: 258 ºC
• Flash Point: 114 ºC
• Appearance: /
• Density: 1.062
• Vapor Pressure: 0.0141mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-methoxy-4-methyl-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-4-methyl-benzaldehyde(57415-35-7)
• EPA Substance Registry System: 2-methoxy-4-methyl-benzaldehyde(57415-35-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 57415-35-7(Hazardous Substances Data)

Usage

Uses

2-Methoxy-4-methylbenzaldehyde acts as a reagent in the synthesis of [3,2-d]pyrimidine derivatives as week as in the synthesis of tachykinin NK2 receptor antagonists which may be used in the treatment of IBS.

InChI:InChI=1/C9H10O2/c1-7-3-4-8(6-10)9(5-7)11-2/h3-6H,1-2H3

Upstream product

• 698-27-1 4-methylsalicylaldehyde 
• 74-88-4 methyl iodide 
• 108-39-4 3-methyl-phenol 
• 1706-11-2 2,5-Dimethyl-anisol 
• 10542-80-0 (2-methoxy-4-methylphenyl)methanol 
• 81245-24-1 methyl 4-methyl-2-methoxybenzoate 
• 115512-67-9 ((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-(2-methoxy-4-methyl-phenyl)-methanone 
• 51671-69-3 2-Methoxy-4-methylbenzoyl chloride 
• 115512-80-6 (2-Methoxy-4-methyl-phenyl)-((S)-2-methoxymethyl-pyrrolidin-1-yl)-methanone 

Downstream Products

• 50-85-1 2-hydroxy-p-toluic acid 
• 5156-00-3 2-methoxyterephthalic acid 
• 52336-48-8 (+/-)-1-(2-methoxy-4-methylphenyl)-2-aminopropane 
• 139102-20-8 2-(2-methoxy-4-methylphenyl)aminoethane 
• 139102-22-0 (+/-)-N-methyl-1-(2-methoxy-4-methylphenyl)-2-aminopropane 
• 139102-35-5 1-(2-methoxy-4-methylphenyl)-2-nitropropene 

Relevant articles and documents

Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls

An efficient electrochemical method for benzylic C(sp3)-H bond oxidation has been developed. A variety of methylarenes, methylheteroarenes, and benzylic (hetero)methylenes could be converted into the desired aryl aldehydes and aryl ketones in moderate to excellent yields in an undivided cell, using O2 as the oxygen source and lutidinium perchlorate as an electrolyte. On the basis of cyclic voltammetry studies, 18O labeling experiments, and radical trapping experiments, a possible single-electron transfer mechanism has been proposed for the electrooxidation reaction.

Volatiles from the xylarialean fungus Hypoxylon invadens

The volatiles emitted by agar plate cultures of the xylarialean fungus Hypoxylon invadens were investigated by use of a closed loop stripping apparatus in combination with GC-MS. Several aromatic compounds were found that could only be identified by comparison to all possible constitutional isomers with different ring substitution patterns. For the set of identified compounds a plausible biosynthetic scheme was suggested that gives further support for the assigned structures.

2-BENZYL-BENZIMIDAZOLE COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp