51679-37-9Relevant academic research and scientific papers
Synthesis of Unsymmetrical Sulfides and Their Oxidation to Sulfones to Discover Potent Antileishmanial Agents
Dar, Ajaz A.,Enjamuri, Nagasuresh,Shadab,Ali, Nahid,Khan, Abu T.
supporting information, p. 671 - 681 (2015/11/17)
Unsymmetrical sulfides were first synthesized using combinations of a 1,3-dicarbonyl, an aromatic aldehyde and a thiol in the presence of 10 mol % ethanolic piperidine. These sulfides derivatives were subsequently converted into corresponding sulfones via
C-H bond oxidation initiated pummerer- And knoevenagel-Type reactions of benzyl sulfide and 1,3-dicarbonyl compounds
Li, Zhiping,Li, Haijun,Guo, Xingwei,Cao, Lin,Yu, Rong,Li, Huanrong,Pan, Shiguang
supporting information; experimental part, p. 803 - 805 (2009/04/06)
A novel Pummerer-type reaction was developed via o-chloranil-mediated C-H bond oxidation. The reaction provides a simple and efficient method to construct sulfide derivatives. A Knoevenagel-type reaction was also achieved via multiple C-H bonds activation under neutral reaction conditions.
