51740-38-6

Upstream product

• 647-42-7 1H,1H,2H,2H-tridecafluoro-n-octanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1224408-59-6 C₁₆H₁₀F₁₃N₃ 
• 1616596-38-3 N-(2-hydroxyethyl)-N,N-dimethyl-3,3,4,4,5,5,6,6,7,7,8,8,8-tride-cafluorooctane-1-ammonium tosylate 
• 34451-26-8 2-perfluorohexylethanethiol 

Relevant academic research and scientific papers

Macrocyclic ligands with partially fluorinated sidearms: Synthesis and metal ion complexation

Derivatives of aza-12-crown-4, aza-15-crown-5, aza-18-crown-6, 1,10- diaza-18-crown-6 and 1,4,8,12-tetraazacyclopentadecane with partially fluorinated substituents attached to nitrogen are prepared. Their efficiencies and selectivities in alkali metal and

Preparation of (perfluoroalkyl)alkane thiols via Zemplén deacylation of fluorous (perfluoroalkyl)alkyl thioacetates

Convenient and robust synthesis of (perfluoroalkyl)alkane thiols [(CnF2n+1(CH2)mSH); m/n = 3/4,6,8,10, 4a-d; m/n = 2/6, 8; m/n = 1/1,2,3,7,8H, 12a-e] was developed starting from commercially available fluorous alcohols (1a-d, 5, 9a-e). The intermediate (perfluoroalkyl)alkyl iodides and/or sulfonates were reacted with potassium thioacetate in DMF, and the resulting thioacetates were deacetylated by a Zemplén analogue reaction. The (perfluoroalkyl)alkane thiols were obtained in good overall yields and high purity.

Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same

A method of making a functionalized fluorinated monomer for use in making oligomers and polymers that can be used to improve surface properties of polymer-derived systems, such as coatings. The method of making a functionalized fluorinated monomer includes reacting at least one fluorinated nucleophilic reactant, such as a fluorinated alcohol, with at least one compound containing at least one epoxide group. Other methods include reaction of a fluorinated alcohol with a cyclic carboxylic anhydride. In another embodiment, a method includes reacting a fluorinated mesylate, tosylate or triflate with an amine, alkoxide or phenoxide. In other embodiments, the method includes reacting a fluorinated alcohol with an alkyl halide, or reacting a fluorinated alkyl halide with an amine. The functionalized fluorinated monomers may be used as intermediates and reacted to modify the functional groups thereon. Further, the functionalized fluorinated monomers may be reacted to form polymers or oligomers, or with polymers or oligomers having functional groups to modify the polymer or oligomer through the functional group thereon,

Fluorinated organic azides-their preparation and synthetic applications

Alkyl azides are widely used in many reactions. Although synthesis of such species is relatively well documented, fluorinated azides, especially with large perfluorinated or highly fluorinated groups, are sometimes tricky to make. The presence of fluorine in reacting molecules, sometimes causes significant changes in the reactivity of reacting species. In this paper we give a short overview of re-examination of currently available methods of synthesis of selected azides with highly fluorinated groups.

Novel fluorinated dialkylphosphonatocholines: Synthesis, physicochemical properties and antiprotozoal activities against Acanthamoeba spp.

The synthesis of four new organophosphorous gemini surfactants is presented. They belong to the class of dialkylphosphonatocholines. Tails are represented with two octyl groups both non or partially fluorinated. The synthesis was performed by reaction of alkylphosphonic acids with choline derivatives in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride. The micellar, surface active, and solubilization properties of new surfactants were studied. Antiprotozoal activities were tested against Acanthamoeba lugdunensis and Acanthamoeba quina.

Light-fluorous TEMPO: reagent, spin trap and stable free radical

The synthesis of two light-fluorous TEMPO derivatives is reported, along with their fluorous-organic solvent partition coefficients and their ESR spectra. Applications of the fluorous-TEMPO reagents in oxidation reactions and as radical traps are discussed.

Novel light-fluorous TEMPO reagents and their application in oxidation reactions

The synthesis of two light-fluorous TEMPO derivatives is reported, along with their application in oxidation reactions.