51757-15-4

Basic information

• Product Name: O²¹,O²³-isopropylidene-O²⁵-deacetyl-O¹,O⁴-didehydro-rifamycin
• CAS NO: 51757-15-4
• Molecular Weight: 693.791
• Mol File: 51757-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O²¹,O²³-isopropylidene-O²⁵-deacetyl-O¹,O⁴-didehydro-rifamycin(CAS DataBase Reference)
• NIST Chemistry Reference: O²¹,O²³-isopropylidene-O²⁵-deacetyl-O¹,O⁴-didehydro-rifamycin(51757-15-4)
• EPA Substance Registry System: O²¹,O²³-isopropylidene-O²⁵-deacetyl-O¹,O⁴-didehydro-rifamycin(51757-15-4)

Safety Data

• Hazardous Substances Data: 51757-15-4(Hazardous Substances Data)

Upstream product

• 62623-68-1 rifamycin S 
• 67-64-1 acetone 

Downstream Products

• 51757-20-1 O²¹,O²³-isopropylidene-25-oxo-25-deacetoxy-O¹,O⁴-didehydro-rifamycin 

Relevant articles and documents

Rifamycin analogs and uses thereof

The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3′-hydroxy analogs, 4′- and/or 6′ halo and/or alkoxy analogs, and various 5′ substituents that incorporate a cyclic amine moiety.