5176-93-2Relevant academic research and scientific papers
A copper-mediated tandem reaction through isocyanide insertion into N-H bonds: Efficient access to unsymmetrical tetrasubstituted ureas
Huang, Xiaomei,Xu, Shuguang,Tan, Qitao,Gao, Mingchun,Li, Minjie,Xu, Bin
supporting information, p. 1465 - 1468 (2014/02/14)
A copper-mediated multi-component reaction was developed through isocyanide insertion into N-H bonds of less active secondary arylamines. This approach leads to an efficient synthesis of unsymmetrical tetrasubstituted ureas in one pot. The Royal Society of Chemistry.
Preparation of the maleic anhydride nucleus from dichloro γ-lactams: Focus on the role of the N-substituent in the functional rearrangement and in the hydrolytic steps
Ghelfi, Franco,Pattarozzi, Mariella,Roncaglia, Fabrizio,Parsons, Andrew F.,Felluga, Fulvia,Pagnoni, Ugo M.,Valentin, Ennio,Mucci, Adele,Bellesia, Franco
experimental part, p. 3131 - 3141 (2009/04/06)
The preparation of the 3,4-dialkyl-substituted maleic anhydride nucleus, through the functional rearrangement of dichloro γ-lactams, allowed the comparison of various N-substituents in the functional rearrangement step. The 2-pyridyl group proved to be the most appropriate N-substituent for the hydrolysis of the 5-methoxy-1,5-dihydro-2H-pyrrol-2-one intermediate into the 5-hydroxy adduct, and for the hydrolysis of the maleimide nucleus into the maleic anhydride. The oxidation of the 5-hydroxy-1,5-dihydro-2H-pyrrol-2-one into the corresponding maleimide was achieved with manganese(IV) oxide. Georg Thieme Verlag Stuttgart.
Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines
Jaime-Figueroa, Saul,Liu, Yanzhou,Muchowski, Joseph M.,Putman, David G.
, p. 1313 - 1316 (2007/10/03)
A series of anilines and heteroarylamines were synthesized in moderate to excellent yields by palladium catalyzed cross coupling reaction of aryl or heteroaryl halides with allyl- or N,N-diallylamine followed by deallylation.
Substituted sulfonylurea, processes for the production of these compounds, as well as compositions containing the same and having herbicidal and plant growth regulating activity
-
, (2008/06/13)
New substituted sulfonyl urea are disclosed of the general formula STR1 in which R1 is chlorine, --COOR5, --S(O)n --R6 or STR2 R2 is STR3 or --CH2 --C C--R11, R3 is hydrogen, C1 -C4 -alkyl, C1 -C4 -alkylthio, halogen, halogen-C1 -C4 -alkyl, halogen-C1 -C4 -alkoxy, Di-C1 -C3 -alkyl-amino, C1 -C3 -alkyl-amino or C1 -C3 -alkoxy-C1 -C3 -alkoxy, R4 is hydrogen C1 -C4 -alkyl, C1 -C4 -alkoxy, C1 -C4 -alkylthio, halogen, halogen-C1 -C4 -alkyl, halogen-C1 -C4 -alkoxy, Di-C1 -C3 -alkyl-amino, C1 -C3 -alkyl-amino, or C1 -C3 -alkoxy-C1 -C3 -alkoxy, Z is --CH= or --N=, R5 is C1 -C8 -alkyl, C3 -C8 -cycloalkyl, C1 -C3 -alkoxy-C1 -C3 -alkyl, phenyl, substituted phenyl, benzene or substituted benzene, R6 is C1 -C6 -alkyl or phenyl, R7 is C1 -C4 -alkyl, R8 is C1 -C4 -alkyl, R7 and R8 are independently C3 -C8 -cycloalkyl, morpholinyl, pyrrolidinyl, piperidyl or piperazinyl, R9 is hydrogen, chlorine, fluorine, or C1 -C3 -alkyl, R10 is hydrogen, chlorine, fluorine, trifluoromethyl or C1 -C3 -alkyl, R11 is hydrogen, chlorine, fluorine, cyano, C1 -C4 -alkyl or phenyl, X is oxygen or sulfur, and n is 0, 1 or 2, as well as processes for the preparation of these compounds and compositions having herbicidal and plant growth regulating effectiveness.
