51760-20-4

Usage

Uses

Used in Organic Synthesis:
1,3-bis(bromoMethyl)-5-nitrobenzene is used as a reagent for the synthesis of various organic compounds due to its reactive bromomethyl groups and the directing effect of the nitro group. This allows for the creation of more complex organic molecules through substitution and aromatic substitution reactions.
Used in Research Laboratories:
In research settings, 1,3-bis(bromoMethyl)-5-nitrobenzene is utilized as a building block for the preparation of intricate organic molecules. Its unique structure and reactivity make it a valuable component in the development of new chemical entities and the study of reaction mechanisms in organic chemistry.

Upstream product

• 13438-30-7 5-nitro-1,3-benzenedicarbonylchloride 
• 99-12-7 5-nitro-m-xylene 
• 81-20-9 2,6-dimethylnitrobenzene 
• 121-91-5 isophthalic acid 
• 108-38-3 m-xylene 
• 36308-36-8 5-nitrobenzene-1,3-dicarbaldehyde 
• 618-88-2 5-nitrobenzene-1,3-dicarboxylic acid 
• 71176-55-1 5-nitro-m-xylene-(α,α')-diol 

Downstream Products

• 90678-53-8 1,3-bis-iodomethyl-5-nitro-benzene 
• 154742-98-0 (3-{[Bis-(2-pyridin-2-yl-ethyl)-amino]-methyl}-5-nitro-benzyl)-bis-(2-pyridin-2-yl-ethyl)-amine 
• 77799-10-1 6-Nitro-18-phenyl-2,11-dithia<3.3>metacyclophan 
• 133753-65-8 (+)-5-Nitro-10-(p-tolylsulfonyl)-1-thia-10-aza<2.2>metacyclophan 
• 133753-66-9 (-)-5-Nitro-10-(p-tolylsulfonyl)-1-thia-10-aza<2.2>metacyclophan 
• 155940-53-7 4-Kaskade:1-nitrobenzol<2-3,5>:(5-(N-tosyl-1-azaethyl)-1,3-phenylen):carbonsaeure-methylester 
• 154742-99-1 [3-({Bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amino}-methyl)-5-nitro-benzyl]-bis-[2-(5-ethyl-pyridin-2-yl)-ethyl]-amine 
• 1379675-80-5 C₁₀H₁₃NO₂S₂ 
• 884341-48-4 3-(dimethylaminomethyl)-5-methylaniline 

Relevant academic research and scientific papers

A Cyclic-RGD Dinuclear TbIII Macrocyclic Complex as a Tumor Integrin-Selective Luminescent Probe

To develop small molecular integrin-selective luminescent imaging probes, we have prepared the binary dipicolinate (DPA) TbIII dinuclear macrocyclic complex, Tb2(cRGDfK-ODO2A-dimer) (DPA)22– or complex I, and reference ligands and TbIII complexes which were purified by HPLC and characterized by NMR, mass spectrometry and luminescence spectroscopy. Luminescence titrations of the structural and bonding model Tb2(m-ODO2A-dimer)2+ complex by DPA2– ion confirmed the molecular formula of the adduct was Tb2(m-ODO2A-dimer)(DPA)22–, and the first binary binding constant was determined to be log K1 = 5.76. At pH 7.4, complex I showed 300 times luminescence enhancement at 544 nm (λex = 278 nm) as compared to that without adding DPA, and was found to bind to αvβ3 integrin and human glioblastoma U87MG tumor cells in both specific and non-specific modes, via luminescence spectroscopic and confocal cell imaging competition studies. This makes complex I and its future optimized derivatives potentially feasible for preclinical bioimaging applications, particularly in the time-resolved mode.

Bimetallic lanthanide complexes derived from macrocycle-appended m-xylyl derivatives: Synthesis and spectroscopic properties

A series of bimetallic lanthanide complexes was prepared from a bimacrocyclic system in which two DO3A units are linked by a m-xylyl unit appended with either a NO2 or an NH2 group (DO3A=1,4,7,10-tetraazacyclododecane-1,4,7-triacetic

Semi-shelled melon ring C containing aniline structure33 H39 O3 N9 Synthesis method and synthesis method thereof

The invention discloses a semi-melon ring C containing an aniline structure. 33 H39 O3 N9 , The C33 H39 O3 N Chemistry name 35 , 75 , 115 - Triamino -1 , 5, 9 (1, 3) - triazoline generation -3 , 7, 11 (1, 3) - triphenyl cyclododecatriene -12 , 52 , 92 ; Trione. C33 H39 O3 N9 The synthesis method of 5 -nitrobenzene -1, 3 - diacid-AONS-3,5 - bis - (bromomethyl) nitrobenzene-AOE286928692X0AO_ 3,5 bis (- 1,3 - (bromomethyl) -5 - 3 - 3,5 - nitrobenzene 3 -2 -) imidazoli -2 -AOE286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869286928692869 5 . 5 , 75 , 115 - Trinitro -1 , 5, 9 (1, 3) - triazoline generation -3 , 7, 11 (1, 3) - triphenyl cyclododecatriene -12 , 52 , 92 - Triketone-AOE 286928692X0AO_ 35 , 75 , 115 - Triamino -1 , 5, 9 (1, 3) - triazoline generation -3 , 7, 11 (1, 3) - triphenyl cyclododecatriene -12 , 52 , 92 ; Trione. C33 H39 O3 N9 Can regard as Fe3 + A detector; and a detector. The utility model can also be used as a detector for nitrophenol substances. The synthesis method has the characteristics of simplicity, rapidness, easiness in operation, low cost and the like.

Synthesis of a novel aminobenzene-containing hemicucurbituril and its fluorescence spectral properties with ions

A novel hemicucurbituril-based macrocycle, alternately consisting of amidobenzene and 2-imidazolidione moieties was designed and synthesized. Based on the fragment coupling strategy, nitrobenzene-containing hemicucurbituril was firstly prepared facilely u

Liquid-Crystalline Star-Shaped Supergelator Exhibiting Aggregation-Induced Blue Light Emission

A family of closely related star-shaped stilbene-based molecules containing an amide linkage are synthesized, and their self-assembly in liquid-crystalline and gel states was investigated. The number and position of the peripheral alkyl tails were systematically varied to understand the structure-property relation. Interestingly, one of the molecules with seven peripheral chains was bimesomorphic, exhibiting columnar hexagonal and columnar rectangular phases, whereas the rest of them stabilized the room-temperature columnar hexagonal phase. The self-assembly of these molecules in liquid-crystalline and organogel states is extremely sensitive to the position and number of alkoxy tails in the periphery. Two of the compounds with six and seven peripheral tails exhibited supergelation behavior in long-chain hydrocarbon solvents. One of these compounds with seven alkyl chains was investigated further, and it has shown higher stability and moldability in the gel state. The xerogel of the same compound was characterized with the help of extensive microscopic and X-ray diffraction studies. The nanofibers in the xerogel are found to consist of molecules arranged in a lamellar fashion. Furthermore, this compound shows very weak emission in solution but an aggregation-induced emission property in the gel state. Considering the dearth of solid-state blue-light-emitting organic materials, this molecular design is promising where the self-assembly and emission in the aggregated state can be preserved. The nonsymmetric design lowers the phase-transition temperatures.The presence of an amide bond helps to stabilize columnar packing over a long range because of its polarity and intermolecular hydrogen bonding in addition to promoting organogelation.

A phosphonic acid appended naphthalene diimide motif for self-assembly into tunable nanostructures through molecular recognition with arginine in water

A naphthalene diimide motif bearing phosphonic acid functionalities has been found to be self-assembled with l- and d-arginine through chirality induced molecular recognitions and leads to the formation of micrometre long nanobelts and spherical aggregates at pH 9 in water, respectively.

Caged CO2 for the Direct Observation of CO2-Consuming Reactions

CO2-consuming reactions, in particular carboxylations, play important roles in technical processes and in nature. Their kinetic behavior and the reaction mechanisms of carboxylating enzymes are difficult to study because CO2 is inconvenient to handle as a gas, exists in equilibrium with bicarbonate in aqueous solution, and typically yields products that show no significant spectroscopic differences from the reactants in the UV/Vis range. Here we demonstrate the utility of 3-nitrophenylacetic acid and related compounds (caged CO2) in conjunction with infrared spectroscopy as widely applicable tools for the investigation of such reactions, permitting convenient measurement of the kinetics of CO2 consumption. The use of isotopically labeled caged CO2 provides a tool for the assignment of infrared absorption bands, thus aiding insight into reaction intermediates and mechanisms.

Organogelators derived from [3.3]metacyclophane skeleton with a urea unit

Dithia[3.3]metacyclophanes with a urea unit having long alkyl chains have been prepared. It has been found out that some of them give stable organogels in some solvents, and their gelating ability depends on structural properties of both aromatic componen

Efficient synthetic access to cationic dendrons and their application for ZnO nanoparticles surface functionalization: New building blocks for dye-sensitized solar cells

A new concept for the efficient synthesis of cationic dendrons, 4-tert-butyl-1-(3-(3,4-dihydroxybenzamido)benzyl)pyridinium bromide (17), 1,1′-(5-(3,4-dihydroxybenzamido)-1,3-phenylene)bis(methylene) bis(4-tert-butylpyridinium) bromide (18), N1,N7-bis(3-(

Synthesis and spectroscopic studies on azo-dye derivatives of polymetallic lanthanide complexes: Using diazotization to link metal complexes together

(Graph Presented) Heteronuclear tetrametallic lanthanide complexes have been synthesized from stable complexes by diazotization and azo-compound formation. Luminescence spectroscopy has been used to show that the complexes used as building blocks are stab