51763-58-7Relevant academic research and scientific papers
Synthesis of 2'-C-cyano-2'-deoxy- And 2'-C-cyano-2',3'-dideoxy-β-D-arabinofuranosyl Nucleosides
Velazquez, Sonsoles,Camarasa, Maria-Jose
, p. 1683 - 1694 (2007/10/02)
A series of 2'-C-cyano-2'-deoxy- and 2'-C-cyano-2',3'-dideoxy arabinofuranosyl nucleosides have been prepared by reaction of the corresponding 2'-ulosyl- and 3'-deoxy-2'-ulosyl nucleosides with sodium cyanide followed by 2'-deoxygenation of the cyanohydri
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: A structure-activity analysis
Herdewijn,Pauwels,Baba,Balzarini,De Clercq
, p. 2131 - 2137 (2007/10/02)
A systematic synthesis was undertaken of 2',3'-dideoxyadenosine analogues with either an azido, fluorine, or hydroxyl group substituted in the 'up' or 'down' position of C-2 or C-3 of the sugar moiety. The compounds were evaluated against the cytopathogen
