2627-64-7Relevant articles and documents
NEW 2' AND/OR 5' AMINO-ACID ESTER PHOSPHORAMIDATE 3'-DEOXY ADENOSINE DERIVATIVES AS ANTI-CANCER COMPOUNDS
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Page/Page column 57, (2016/06/14)
The present invention relates to chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours inhomo sapiens. The compounds are derivatives of cordycepin (3'-deoxyadenosine) having a 2' and/or 5'- amino-acid ester phosphoramidate moeity.
Nucleic acid related compounds.22. Transformation of ribonucleoside 2,3'-O-ortho esters into halo, deoxy, and epoxy sugar nucleosides using acyl halides. Mechanism and structure of products.
Robins,Mengel,Jones,Fouron
, p. 8204 - 8213 (2007/10/04)
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