51784-41-9Relevant academic research and scientific papers
Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents
Salehi, Naeimeh,Mirjalili, Bi Bi Fatemeh,Nadri, Hamid,Abdolahi, Zahra,Forootanfar, Hamid,Samzadeh-Kermani, Alireza,Kü?ükk?l?n?, Tuba Tüylü,Ayazgok, Beyza,Emami, Saeed,Haririan, Ismaeil,Sharifzadeh, Mohammad,Foroumadi, Alireza,Khoobi, Mehdi
, p. 559 - 568 (2018/11/26)
A novel series of benzylpyridinium-based benzoheterocycles (benzimidazole, benzoxazole or benzothiazole) were designed as potent acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors. The title compounds 4a-q were conveniently synthesiz
4-Heterocyclyl tetrahydropyridines as selective ligands for the human dopamine D4 receptor.
Haworth,Harrison,Kulagowski,Leeson,Owens,Ridgill,Teall,Fielding,Chapman,Emms,Marwood,Patel,Moss
, p. 2211 - 2216 (2007/10/03)
A series of 1,2,3,6-tetrahydropyridines 3 were synthesised, which resulted in selective high affinity dopamine D4 ligands. The SAR of heterocyclic replacements and aromatic substitution was investigated, leading to compounds of nanomolar bindin
