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Benzonitrile, 2-chloro-3-hydroxy-, also known as 2-chloro-3-cyanophenol, is a chemical compound with the molecular formula C7H4ClNO. It is a derivative of benzonitrile and exists as a colorless to pale yellow solid with a molecular weight of 153.566 g/mol. Benzonitrile, 2-chloro-3-hydroxyis known for its biological activity, particularly as an anti-cancer agent and an inhibitor of tyrosine-protein kinases. However, it requires careful handling and management due to potential harmful effects on human health and the environment.

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  • 51786-11-9 Structure
  • Basic information

    1. Product Name: Benzonitrile, 2-chloro-3-hydroxy-
    2. Synonyms: Benzonitrile, 2-chloro-3-hydroxy-;2 - chloro - 3 - cyanophenol
    3. CAS NO:51786-11-9
    4. Molecular Formula: C7H4ClNO
    5. Molecular Weight: 153.57
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 51786-11-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 273.7±25.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.41±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Inert atmosphere,Room Temperature
    8. Solubility: N/A
    9. PKA: 7.11±0.10(Predicted)
    10. CAS DataBase Reference: Benzonitrile, 2-chloro-3-hydroxy-(CAS DataBase Reference)
    11. NIST Chemistry Reference: Benzonitrile, 2-chloro-3-hydroxy-(51786-11-9)
    12. EPA Substance Registry System: Benzonitrile, 2-chloro-3-hydroxy-(51786-11-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 51786-11-9(Hazardous Substances Data)

51786-11-9 Usage

Uses

Used in Pharmaceutical Industry:
Benzonitrile, 2-chloro-3-hydroxyis used as an intermediate in the synthesis of various pharmaceuticals for its potential therapeutic applications. Its anti-cancer properties make it a valuable component in the development of new drugs targeting cancer treatment.
Used in Agrochemical Industry:
Benzonitrile, 2-chloro-3-hydroxyalso serves as an intermediate in the production of agrochemicals, contributing to the development of pesticides and other agricultural chemicals that enhance crop protection and yield.
Used in Dye Production:
Benzonitrile, 2-chloro-3-hydroxyis utilized in the manufacturing process of dyes, where its chemical properties contribute to the creation of a diverse range of colorants for various industries.
Used in Organic Compounds Synthesis:
As a versatile chemical intermediate, Benzonitrile, 2-chloro-3-hydroxyis employed in the synthesis of other organic compounds, expanding its applications across different sectors in the chemical industry.
It is crucial to handle Benzonitrile, 2-chloro-3-hydroxywith care, considering its potential harmful effects on human health and the environment, and to adhere to proper safety and management protocols during its use in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 51786-11-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,7,8 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 51786-11:
(7*5)+(6*1)+(5*7)+(4*8)+(3*6)+(2*1)+(1*1)=129
129 % 10 = 9
So 51786-11-9 is a valid CAS Registry Number.

51786-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-3-hydroxybenzonitrile

1.2 Other means of identification

Product number -
Other names 2-CHLORO-3-CYANOPHENOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51786-11-9 SDS

51786-11-9Relevant articles and documents

4 -AMINO -7,8- DIHYDROPYRIMIDO [5, 4 - F] [1, 4] OXAZEPIN- 5 ( 6H) - ONE BASED DGAT1 INHIBITORS

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Page/Page column 105, (2011/10/13)

DGAT-1 inhibitor compounds of formula (I), pharmaceutically-acceptable salts and pro- drugs thereof are described, together with pharmaceutical compositions, processes for making them and their use in treating, for example, diabetes and obesity wherein, R1, R2, R3, R4, X2, q, Y1, Y2, n, Q and Z are as defined in the description.

INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP)

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Page/Page column 146, (2010/06/15)

The present invention relates to novel heterocyclic compounds as Fatty Acid Binding Protein ("FABP") inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the present invention is shown below: (I)

Substituted triazole derivatives as oxytocin antagonists

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Page/Page column 36, (2008/06/13)

The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said compounds. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction.

Evaluation of Potent and Selective Small-Molecule Antagonists for the CXCR2 Chemokine Receptor

Widdowson, Katherine L.,Elliott, John D.,Veber, Daniel F.,Nie, Hong,Rutledge, Melvin C.,McCleland, Brent W.,Xiang, Jia-Ning,Jurewicz, Anthony J.,Hertzberg, Robert P.,Foley, James J.,Griswold, Don E.,Martin, Lenox,Lee, Judithann M.,White, John R.,Sarau, Henry M.

, p. 1319 - 1321 (2007/10/03)

N,N′-Diarylureas were prepared, and the structure-activity relationship relative to the CXCR2 receptor was examined. This led to the identification of a potent and highly selective CXCR2 antagonist, which in addition was shown to be functionally active bo

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