51789-21-0

Basic information

• Product Name: 1-(4-fluorophenyl)-2-phenylhydrazine
• Synonyms: 1-(4-fluorophenyl)-2-phenylhydrazine
• CAS NO: 51789-21-0
• Molecular Weight: 202.231
• Mol File: 51789-21-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(4-fluorophenyl)-2-phenylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluorophenyl)-2-phenylhydrazine(51789-21-0)
• EPA Substance Registry System: 1-(4-fluorophenyl)-2-phenylhydrazine(51789-21-0)

Safety Data

• Hazardous Substances Data: 51789-21-0(Hazardous Substances Data)

Upstream product

• 1545-83-1 4-fluoroazobenzene 
• 371-40-4 4-fluoroaniline 
• 62-53-3 aniline 
• 332-00-3 (E)-1-(4-fluorophenyl)-2-phenyldiazene 

Downstream Products

• 332-00-3 (E)-1-(4-fluorophenyl)-2-phenyldiazene 
• 1545-83-1 4-fluoroazobenzene 

Relevant articles and documents

Convenient semihydrogenation of azoarenes to hydrazoarenes using H2

The high atom-economical and eco-benign nature of hydrogenation reactions make them much more superior to conventional reduction and transfer hydrogenation. Herein, a convenient and highly selective hydrogenation reaction of azoarenes using molecular hydrogen to access diverse hydrazoarenes is reported. The present catalytic method is general and operationally simple, and it operates under exceedingly mild conditions (room temperature and 1 atm of hydrogen pressure). The reusability of catalysts used in this method is also successfully demonstrated.

Visible-Light-Promoted Diboron-Mediated Transfer Hydrogenation of Azobenzenes to Hydrazobenzenes

A visible-light-promoted transfer hydrogenation of azobenzenes has been developed. In the presence of B2pin2 and upon visible-light irradiation, the reactions proceeded smoothly in methanol at ambient temperature. The azobenzenes with diverse functional groups have been reduced to the corresponding hydrazobenzenes with a yield of up to 96%. Preliminary mechanistic studies indicated that the hydrogen atom comes from the solvent and the transformation is achieved through a radical pathway.

Dehydrogenation of the NH?NH Bond Triggered by Potassium tert-Butoxide in Liquid Ammonia

A novel strategy for the dehydrogenation of the NH?NH bond is disclosed using potassium tert-butoxide (tBuOK) in liquid ammonia (NH3) under air at room temperature. Its synthetic value is well demonstrated by the highly efficient synthesis of aromatic azo compounds (up to 100 % yield, 3 min), heterocyclic azo compounds, and dehydrazination of phenylhydrazine. The broad application of this strategy and its benefit to chemical biology is proved by a novel, convenient, one-pot synthesis of aliphatic diazirines, which are important photoreactive agents for photoaffinity labeling.