51801-03-7Relevant academic research and scientific papers
Formation of symmetrical alkenes by homocoupling of metallated sulfones under nickel catalysis
Gai, Yonghua,Julia, Marc,Jean-Noe,Verpeaux
, p. 805 - 816 (2007/10/03)
Summary -Allylic sulfones undergo a coupling reaction with organometallic compounds (Mg or Li) not only with copper catalysts but also with iron or nickel salts. With 7,7-disubstituted allylic sulfones and also saturated aliphatic sulfones, however, another reaction was observed whereby two molecules of the starting sulfone are coupled to give symmetrical alkenes. The scope of this reaction was investigated. Elsevier.
Sulphoxide Substituted Pyridines as Phase-transfer Catalysts for Nucleophilic Displacements and Alkylations
Furukawa, Naomichi,Ogawa, Satoshi,Kawai, Tsutomu,Oae, Shigeru
, p. 1833 - 1838 (2007/10/02)
2-Methylsulphinyl-, 2-methylsulphinylmethyl-, 2,6-bis(methylsulphinyl)-, 2,6-bis(methylsulphinylmethyl)-pyridines, bis(2-pyridylmethyl)sulphoxide, and 2-methylsulphinylpyridine N-oxide have been prepared.These sulphoxides served as good phase-transfer catalysts which accelerate SN2 type displacements of octyl bromide with various nucleophiles (thiolate, cyanide, thiocyanate, and phenoxide) in solid-liquid two-phase systems.Alkylations of phenylacetonitrile and benzyl methyl ketone with alkyl halides were also carried out in liquid-liquid two-phase systems in the presence of the above sulphoxides to afford the corresponding monoalkylated products in high yields.Pyridine derivatives bearing polysulphinyl groups were found to be even more effective catalysts for these two-phase alkylations.Neither 2-methylthio- nor 2-methylsulphonyl-pyridine catalysed SN2 type displacement reactions effectively.
ORGANIC SULFUR COMPOUNDS CONTAINING HETEROCYCLES. II: METHYL 2-PYRIDYL SULFOXIDE AS PHASE TRANSFER CATALYST.
Furukawa, Naomichi,Kishimoto, Keiko,Ogawa, Satoshi,Kawai, Tsutomu,Fujihara, Hisashi,Oae, Shigeru
, p. 4409 - 4412 (2007/10/02)
Methyl 2-pyridyl sulfoxide was found to be an excellent phase transfer catalyst which promotes simple SN2 type displacement reactions of alkyl halides with some nucleophiles.
