518050-99-2Relevant academic research and scientific papers
Synthesis of some diazino-fused tricyclic systems via Suzuki cross-coupling and regioselective nitrene insertion reactions
Tapolcsányi, Pál,Krajsovszky, Gábor,Andó, Rómeó,Lipcsey, Péter,Horváth, Gyula,Mátyus, Péter,Riedl, Zsuzsanna,Hajós, Gy?rgy,Maes, Bert U. W.,Lemière, Guy L. F.
, p. 10137 - 10143 (2002)
Suzuki coupling of 5-chloro-2-methyl-6-phenylpyridazin-3(2H)-one, 6-chloro-1,3-dimethyluracil and 2-chloropyrazine with protected aminoaryl boronic acids resulted in the corresponding pivaloylaminophenyl diazines which were transformed to diazino-fused indole and cinnoline derivatives. Suzuki coupling of 5-amino-6-chloro-1,3-dimethyluracil with 2-formylphenyl boronic acid afforded a novel pyrimidoisoquinoline ring system in a one-pot reaction.
