51812-96-5 Usage
General Description
4-Mercaptoquinoline, also known as 4-Methioquinolin, is a chemical compound with the molecular formula C9H7NS. It is a heterocyclic aromatic compound containing a quinoline ring and a sulfur atom. 4-Mercaptoquinoline has a wide range of applications in the pharmaceutical and chemical industries due to its ability to form complexes with various metal ions. It is used as a chelating agent in the treatment of metal poisoning and as an intermediate in the synthesis of pharmaceutical drugs. Additionally, it has been studied for its potential anti-cancer and anti-microbial properties. 4-Mercaptoquinoline is considered a hazardous substance and should be handled with caution due to its toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 51812-96-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,8,1 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 51812-96:
(7*5)+(6*1)+(5*8)+(4*1)+(3*2)+(2*9)+(1*6)=115
115 % 10 = 5
So 51812-96-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NS/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11)
51812-96-5Relevant articles and documents
Discovery of potent and orally bioavailable inhibitors of Human Uric Acid Transporter 1 (hURAT1) and binding mode prediction using homology model
Peng, Jianbiao,Hu, Qiyue,Gu, Chunyan,Liu, Bonian,Jin, Fangfang,Yuan, Jijun,Feng, Jun,Zhang, Lei,Lan, Jiong,Dong, Qing,Cao, Guoqing
supporting information, p. 277 - 282 (2016/01/09)
This Letter describes the discovery of a series of potent inhibitors of Human Uric Acid Transporter 1 (hURAT1). Lead generation and optimization via 3D pharmacophore analysis resulted in compound 41. With an IC50 of 33.7 nM, 41 also demonstrated good oral bioavailability in rat (74.8%) and displayed a consistent PK profile across all species tested (rat, dog and monkey).
Simple Syntheses of Aryl Alkyl Thioethers and of Aromatic Thiols from Unactivated Aryl Halides and Efficient Methods for Selective Dealkylation of Aryl Alkyl Ethers and Thioethers
Testaferri, L.,Tiecco, M.,Tingoli, M.,Chianelli, D.,Montanucci, M.
, p. 751 - 755 (2007/10/02)
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