518316-79-5

Downstream Products

• 518316-81-9 (1S,2R,4S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2-ethyl-6-methyl-1-(toluene-4-sulfonylmethyl)-cyclohexanol 
• 518316-83-1 (1S,2R,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2-ethyl-6-methyl-1-(toluene-4-sulfonylmethyl)-cyclohexanol 
• 518316-80-8 (1S,2R,4S,6S)-2-Ethyl-6-methyl-1-(toluene-4-sulfonylmethyl)-cyclohexane-1,4-diol 
• 518316-82-0 (1S,2R,4R,6S)-2-Ethyl-6-methyl-1-(toluene-4-sulfonylmethyl)-cyclohexane-1,4-diol 

Relevant academic research and scientific papers

β-hydroxysulfoxides as chiral cyclic ketone equivalents: Enantioselective synthesis of polysubstituted cyclohexanones, cyclohexenones and cyclohexenediones

The β-hydroxysulfoxide moiety, after oxidation to sulfone, acts as a masked carbonyl group in a cyclic system, opening an easy access to differently substituted enantiomerically pure cyclic ketones by means of aluminium-mediated conjugate additions, stereoselective reductions and elimination by retrocondensation in basic medium.