51865-09-9

Basic information

• Product Name: Phosphonothioic acid, methyl-, O-ethyl S-methyl ester
• CAS NO: 51865-09-9
• Molecular Formula: C4H11O2PS
• Molecular Weight: 154.17
• Mol File: 51865-09-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonothioic acid, methyl-, O-ethyl S-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonothioic acid, methyl-, O-ethyl S-methyl ester(51865-09-9)
• EPA Substance Registry System: Phosphonothioic acid, methyl-, O-ethyl S-methyl ester(51865-09-9)

Safety Data

• Hazardous Substances Data: 51865-09-9(Hazardous Substances Data)

Upstream product

• 141-52-6 sodium ethanolate 
• 58259-60-2 methylphosphonothioic acid O,S-dimethyl ester 

Downstream Products

• 683-08-9 Diethyl methylphosphonate 
• 103687-37-2 S-ethyl methylphosphonate 
• 103687-38-3 R-(+) ethyl methylphosphonate 

Relevant articles and documents

STEREOCHEMISTRY OF SOME REACTIONS BETWEEN ALKYL S-METHYL METHYLPHOSPHONOTHIOATES AND CHIRAL ALKOXIDES

With R-(+) ethyl (or methyl) S-methyl methylphosphonothioate and (+)-pinacolyl alkoxide competitive and highly stereoselective displacements of O-alkyl and S-methyl occur, both reactions being with inversion of configuration.With the enantiomeric S-(-) ethyl (and methyl) S-methyl methylphosphonothioates and (+)-pinacolyl alkoxide the reactions, although still competitive, are no longer stereoselective.In contrast similar reactions with the sodium salt of (-)-menthol, (which might be considered to be the mirror image of (+)-pinacolyl alkoxide) occur highly stereoselectively with the S-(-) but not with R-(+) enantiomers.The displacement of O-alkyl from alkyl S-methyl methylphosphonothioates by ethoxide, pinacolyl alkoxide and menthyl alkoxide is not observed when methoxide is the nucleophile; in this case only displacement of S-alkyl group occurs.