51903-64-1

Basic information

• Product Name: 3-(TRIFLUOROMETHYL)-4-METHYLPHENYL ISOC&
• Synonyms: 3-(TRIFLUOROMETHYL)-4-METHYLPHENYL ISOC&;4-METHYL-3-(TRIFLUOROMETHYL)PHENYLISOCYANATE, 97% MIN.;3-(Trifluoromethyl)-4-methylphenyl isocyanate ,97%;4-Isocyanato-1-methyl-2-(trifluoromethyl)benzene;4-Methyl-3-(trifluoromethyl)phenyl isocyanate 97%;4-Isocyanato-1-methyl-2-(trifluoromethyl)benzene, 5-Isocyanato-alpha,alpha,alpha-trifluoro-o-xylene
• CAS NO: 51903-64-1
• Molecular Formula: C₉H₆F₃NO
• Molecular Weight: 201.15
• Product Categories: Phenyl isocyanate&Phenyl isothiocyanate;Isocyanates;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 51903-64-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 190-191 °C(lit.)
• Flash Point: 175 °F
• Appearance: /
• Density: 1.288 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.423mmHg at 25°C
• Refractive Index: n20/D 1.4800(lit.)
• CAS DataBase Reference: 3-(TRIFLUOROMETHYL)-4-METHYLPHENYL ISOC&(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(TRIFLUOROMETHYL)-4-METHYLPHENYL ISOC&(51903-64-1)
• EPA Substance Registry System: 3-(TRIFLUOROMETHYL)-4-METHYLPHENYL ISOC&(51903-64-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38-42
• Safety Statements: 23-26-36-45
• RIDADR: UN 2206 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 51903-64-1(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Uses

4-Methyl-3-(trifluoromethyl)phenylisocyanate

InChI:InChI=1/C9H6F3NO/c1-6-2-3-7(13-5-14)4-8(6)9(10,11)12/h2-4H,1H3

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 65934-74-9 3-(trifluoromethyl)-4-methylaniline 

Downstream Products

• 1347008-73-4 1-(2-chloro-4-(2-(5-(trifluoromethyl)-1H-imidazol-2-yl)pyridin-4-yloxy)phenyl)-3-(4-methyl-3-(trifluoromethyl)phenyl)urea 
• 847024-27-5 1-(4-methyl-3-trifluoromethyl-phenyl)-3-(3-{8-[(pyridin-4-yl-methyl)-amino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-urea 
• 1026988-03-3 1-(3-formylphenyl)-3-(4-methyl-3-trifluoromethylphenyl)urea 

Relevant articles and documents

COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF

The present invention provides compounds that modulate protein function, to restore protein homeostasis, including cytokine, CK1α, GSPT1, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of diseases, disorders, or conditions associated with a protein, such as diseases, disorders, and conditions associated with cytokines, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer's disease, and cancer, are provided.