Welcome to LookChem.com Sign In|Join Free
  • or
1H-Indole-1-carboxylic acid, 5-[(4-Methyl-1-piperazinyl)sulfonyl]-, 1,1-diMethylethyl ester is a chemical compound that serves as a pharmaceutical intermediate. It is a derivative of indole-1-carboxylic acid, which is recognized for its potential therapeutic applications. 1H-Indole-1-carboxylic acid, 5-[(4-Methyl-1-piperazinyl)sulfonyl]-, 1,1-diMethylethyl ester's stability and suitability for pharmaceutical use are enhanced by the presence of the 1,1-diMethylethyl ester group. Furthermore, the 4-Methyl-1-piperazinyl sulfonyl group imparts specific pharmacological properties to the compound, making it a valuable asset in the development of novel drugs. This chemical entity holds substantial promise in pharmaceutical research and development.

519148-73-3

Post Buying Request

519148-73-3 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

519148-73-3 Usage

Uses

Used in Pharmaceutical Industry:
1H-Indole-1-carboxylic acid, 5-[(4-Methyl-1-piperazinyl)sulfonyl]-, 1,1-diMethylethyl ester is utilized as a pharmaceutical intermediate for its potential therapeutic uses. 1H-Indole-1-carboxylic acid, 5-[(4-Methyl-1-piperazinyl)sulfonyl]-, 1,1-diMethylethyl ester's stability and specific pharmacological properties make it a key component in the formulation of new drugs, contributing to the advancement of medicinal chemistry and drug discovery efforts.

Check Digit Verification of cas no

The CAS Registry Mumber 519148-73-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,9,1,4 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 519148-73:
(8*5)+(7*1)+(6*9)+(5*1)+(4*4)+(3*8)+(2*7)+(1*3)=163
163 % 10 = 3
So 519148-73-3 is a valid CAS Registry Number.

519148-73-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 5-(4-methylpiperazin-1-yl)sulfonylindole-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-Butyl 5-((4-methylpiperazin-1-yl)sulfonyl)-1H-indole-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:519148-73-3 SDS

519148-73-3Downstream Products

519148-73-3Relevant academic research and scientific papers

Optimization of the indolyl quinolinone class of KDR (VEGFR-2) kinase inhibitors: Effects of 5-amido- and 5-sulphonamido-indolyl groups on pharmacokinetics and hERG binding

Fraley, Mark E.,Arrington, Kenneth L.,Buser, Carolyn A.,Ciecko, Patrice A.,Coll, Kathleen E.,Fernandes, Christine,Hartman, George D.,Hoffman, William F.,Lynch, Joseph J.,McFall, Rosemary C.,Rickert, Keith,Singh, Romi,Smith, Sheri,Thomas, Kenneth A.,Wong, Bradley K.

, p. 351 - 355 (2004)

Modifications to the basic side-chain of early lead structures of the indolyl quinolinone class of KDR kinase inhibitors resulted in improved pharmacokinetic and ancillary profiles. Specifically, compounds bearing 5-amido- and 5-sulphonamido-indolyl substituents exhibited lower plasma clearance and weaker binding affinity for the IKr potassium channel hERG. 2003 Elsevier Science Ltd. All rights reserved.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 519148-73-3