51964-23-9 Usage
General Description
3-(4-chlorophenyl)-1,3-thiazolidine-2,4-dione, also known as Pioglitazone, is a medication used to treat type 2 diabetes. It belongs to the class of thiazolidinedione drugs, which work by increasing the sensitivity of muscle and fat cells to insulin, allowing the body to better regulate blood sugar levels. Pioglitazone is specifically designed to help control high blood sugar in people with type 2 diabetes, particularly those who are unable to manage their condition through diet and exercise alone. This chemical works by targeting the peroxisome proliferator-activated receptor gamma (PPAR-γ), a protein found in fat cells that regulates the expression of genes involved in glucose and fat metabolism. Pioglitazone is available in tablet form and is usually taken once daily, either with or without food, as prescribed by a healthcare professional. As with any medication, there are potential side effects and risks associated with Pioglitazone, so it is important to consult with a doctor before starting or adjusting treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 51964-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,9,6 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 51964-23:
(7*5)+(6*1)+(5*9)+(4*6)+(3*4)+(2*2)+(1*3)=129
129 % 10 = 9
So 51964-23-9 is a valid CAS Registry Number.
51964-23-9Relevant academic research and scientific papers
Reaction of O-alkyl-N-substituted iminothiocarbonates with bromoacetyl bromide. A general method for the synthesis of 3-substituted 1,3-thiazolidine-2,4-diones
Imrich, Jan,Bernat, Juraj,Kristian, Pavol,Busov, Tatiana,Hocova, Slavka
, p. 432 - 436 (2007/10/03)
Reaction of sodium salts of O-methyl-N-substituted iminothiocaibonates with bromoacetyl bromide represents a new general method for preparation of 3-substituted 1,3-thiazolidine-2,4-diones in good yields and high purity. The structure of the synthesized products has been confirmed by 1H NMR, 13C NMR, IR and mass spectroscopy as well as by independent synthesis.
