51978-87-1Relevant academic research and scientific papers
Synthesis of 4-Organoselanyl-1H-pyrazoles: Oxone -Mediated Electrophilic Cyclization of α,β-Alkynyl Hydrazones by Using Diorganyl Diselenides
Perin, Gelson,Nobre, Patrick C.,Mailahn, Daniela H.,Silva, Márcio S.,Barcellos, Thiago,Jacob, Raquel G.,Lenard?o, Eder J.,Santi, Claudio,Roehrs, Juliano A.
, p. 2293 - 2304 (2019)
A simple and efficient method for the synthesis of 4organoselanyl-1 H -pyrazoles has been developed, taking place under metal- and halogen-free conditions. Electrophilic species of selenium were easily generated in situ by the reaction of diorganyl diselenides with Oxone in ethanol as solvent in an open-flask at 70 °C. These electrophilic selenium species were employed in the selenylation/cyclization of α,β-alkynyl hydrazones, giving the title compounds in moderate to excellent yields. The final species of selenium obtained from the reaction of diphenyl diselenide with Oxone were characterized by 77 Se NMR spectroscopy and high-resolution mass spectrometry (HRMS).
Competing ene-reactions in the p-oxidation and o-phenylselenylation of phenol with benzeneseleninic acid
Henriksen, Lars
, p. 7057 - 7060 (2007/10/02)
Reaction of phenol with benzeneseleninic acid gives 2-(phenylseleno)- and 2,6-bis(phenylseleno)-1,4-benzoquinone via the corresponding 2- and 2,6-selenylated phenols; initiating ene-reactions are suggested for both the o-selenylation and the p-oxidation sequence.
