51983-61-0Relevant academic research and scientific papers
Direct Access to β-Trifluoromethyl-β-hydroxy Thioesters by Biomimetic Organocatalytic Enantioselective Aldol Reaction
Park, Jin Hyun,Sim, Jae Hun,Song, Choong Eui
, p. 4567 - 4570 (2019)
A broadly applicable biomimetic enantioselective decarboxylative catalytic aldol reaction of trifluoromethyl ketones with malonic acid half-thioesters (MAHTs) is described. Utilizing cinchona-based thioureas as highly efficient polyketide synthase-mimic c
