51985-10-5Relevant academic research and scientific papers
Pd-catalyzed decarbonylative heck olefination of aromatic carboxylic acids activated in situ with di-tert-butyl dicarbonate
Goo?en, Lukas J.,Paetzold, Jens,Winkel, Lars
, p. 1721 - 1723 (2002)
The first protocol for a direct Heck olefination of aromatic carboxylic acids has been developed. By treatment with commercially available di-tert-butyl dicarbonate, the carboxylic acids are converted in situ into the mixed anhydrides, which in the presen
Decarbonylative Heck olefination of enol esters: Salt-free and environmentally friendly access to vinyl arenes
Goossen, Lukas J.,Paetzold, Jens
, p. 1095 - 1098 (2007/10/03)
Thank you, no salt on the side. In this variant of the Heck olefination, enol esters serve as environmentally friendly synthetic equivalents of aryl halides. These reactants, in turn, are available from a waste-free synthesis from carboxylic acids and propyne. Thus, a salt-free overall process has been devised for preparing vinyl arenes from a variety of aromatic carboxylic acids.
