52003-20-0 Usage
Uses
Used in Pharmaceutical Industry:
2-nitrothiophen-3-amine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence of a nitro group and an amine group allows for the development of new drugs with unique therapeutic properties. The reactivity of the nitro group can be utilized to form various functional groups, while the amine group can be used to create amide, urea, or other linkages with other molecules, enhancing the drug's efficacy and selectivity.
Used in Dye Industry:
2-nitrothiophen-3-amine is used as a building block for the production of dyes. The presence of the nitro group and the heterocyclic thiophene ring provides a range of colors and properties to the resulting dyes. 2-nitrothiophen-3-amine can be used to synthesize azo dyes, which are widely used in various applications such as textiles, plastics, and printing inks.
Used in Agrochemical Industry:
2-nitrothiophen-3-amine is used as a precursor in the synthesis of agrochemicals, including pesticides and herbicides. 2-nitrothiophen-3-amine's reactivity and functional groups can be utilized to create new molecules with improved activity and selectivity against pests and weeds. Additionally, the amine group can be used to form salts or complexes with metal ions, enhancing the stability and effectiveness of the agrochemicals.
Used in Organic Synthesis:
2-nitrothiophen-3-amine is used as a versatile building block in organic synthesis. The nitro group can be reduced to an amine or hydroxylamine, allowing for the formation of various functional groups and derivatives. The amine group can be acylated, alkylated, or used in condensation reactions, providing a wide range of synthetic pathways and applications in the preparation of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 52003-20-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,0 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 52003-20:
(7*5)+(6*2)+(5*0)+(4*0)+(3*3)+(2*2)+(1*0)=60
60 % 10 = 0
So 52003-20-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O2S/c5-3-1-2-9-4(3)6(7)8/h1-2H,5H2
52003-20-0Relevant articles and documents
Benzimidazole compounds
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, (2008/06/13)
Novel imidazoles of the formula STR1 and their non-toxic, pharmaceutically acceptable salts with acids and bases having an antagonistic activity against angiotensin II receptors.
Alkylaminonitrobenzenes by Vicarious Nucleophilic Amination with 4-(Alkylamino)-1,2,4-triazoles
Katritzky, Alan R.,Laurenzo, Kathleen S.
, p. 3978 - 3982 (2007/10/02)
A series of 4-(alkylamino)-1,2,4-triazoles transfer the alkylamino group to the 4-position of nitrobenzene and various 3-substituted nitrobenzenes, with no detectable ortho substitution.By contrast 2-nitrothiophene reacts in the 3-position and 2-nitronaphthalene in the 1-position; 1-nitronaphthalene gives a mixture of products derived from dominant 2- with some 4-substitution.The orientations are discussed and rationalized.
Synthesis and pharmacological properties of N-thienyl alkylenediamines
Ronsisvalle, Giuseppe,Pappalardo, Maria S.,Vittorio, Franco,Pasquinucci, Lorella,Caruso, Antonina,et al.
, p. 553 - 560 (2007/10/02)
A series of N-thienylalkylenediamines was synthesized and tested for their analgesic, anti-inflammatory and anti-pyretic activities, as well as for their acute toxicity and central effects.Acetylsalicylic acid, phenylbutazone and indomethacin were used as reference drugs.Several compounds showed interesting aspirin-like properties associated with good systemic and gastric tolerance.Keywords: 2-nitrothiophenes / N-thienyl alkylenediamines / anti-inflammatory activity / analgesic activity / basic anti-inflammatory agents
