52010-50-1Relevant academic research and scientific papers
Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes
Liu, Can,Wang, Zhiming,Wang, Lei,Li, Pinhua,Zhang, Yicheng
, p. 9209 - 9216 (2019)
A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.
Palladium-catalyzed direct C2 arylation of N-substituted indoles with 1-aryltriazenes
Liu, Can,Miao, Tao,Zhang, Lei,Li, Pinhua,Zhang, Yicheng,Wang, Lei
, p. 2584 - 2589 (2014/10/15)
A novel and efficient palladium-catalyzed C2 arylation of N-substituted indoles with 1-aryltriazenes for the synthesis of 2-arylindoles was developed. In the presence of BF3?OEt2 and palladium(II) acetate (Pd(OAc)2), N-substituted indoles reacted with 1-aryltriazenes in N,N-dimethylacetamide (DMAC) to afford the corresponding aryl-indole-type products in good to excellent yields.
