52010-89-6Relevant academic research and scientific papers
LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS
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Page/Page column 81; 82, (2016/03/19)
This invention provides for a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein RA, RB, R2 and R4 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
A Total Synthesis of Paeoveitol
Xu, Lun,Liu, Fengyi,Xu, Li-Wen,Gao, Ziwei,Zhao, Yu-Ming
supporting information, p. 3698 - 3701 (2016/08/16)
A four-step total synthesis of paeoveitol (1), a recently disclosed norditerpene natural product from Paeonia vetchii, is reported. This highly concise synthetic route was guided by biosynthetic considerations and enabled by an unusual intermolecular orth
Evaluation of HIV-1 inhibition by stereoisomers and analogues of the sesquiterpenoid hydroquinone peyssonol A
Treitler, Daniel S.,Li, Zhufang,Krystal, Mark,Meanwell, Nicholas A.,Snyder, Scott A.
supporting information, p. 2192 - 2196 (2013/05/09)
Peyssonol A, a brominated natural product with documented anti-HIV-1 activity, was synthesized racemically along with 6 isomers and 15 truncated analogues and synthetic precursors. These compounds were screened in a cell-based assay against a recombinant
Total synthesis of the fungal metabolite (±)-acremine G: Acceleration of a biomimetic Diels-Alder reaction on silica gel
Mehta, Goverdhan,Khan, Tabrez Babu,Sunil Kumar
scheme or table, p. 5116 - 5119 (2010/11/16)
A total synthesis of the bioactive tetracyclic natural product acremine G has been achieved in which a regio- and stereoselective biomimetic Diels-Alder reaction between two readily assembled building blocks, accelerated on a solid support (silica gel), forms the key step.
