5202-75-5Relevant academic research and scientific papers
Efficient synthesis of symmetrical bisamides from aldehydes and amides catalyzed by silica-bonded S-sulfonic acid nanoparticles
Tajbakhsh, Mahmood,Hosseinzadeh, Rahman,Alinezhad, Heshmatollah,Rezaee, Parizad
supporting information, p. 2370 - 2379 (2013/07/26)
Silica-bonded S-sulfonic acid nanoparticles (SBSSANPs) were easily synthesized from silica nanoparticles and showed to be an efficient catalyst in the synthesis the symmetrical N,N′-alkylidene bisamides. Reaction of aldehydes and amides in the presence of the catalyst afforded the corresponding bisamides in good to excellent yields. The extensive range of substrates suggests general applicability of the method. Reusability of the catalyst, simple workup procedure, and short reaction times are other advantages of this protocol. Copyright
Synthesis of 1-Aminoalkylphosphonic Acids via Amidoalkylation of Phosphorous Acid by N,N'-Alkylidenbisamides
Soroka, Miroslaw,Jaworska, Dorota,Szczesny, Zbigniew
, p. 1153 - 1155 (2007/10/02)
N,N'-Alkylidenebisamides 1, totally unsuitable as amidoalkylating agents toward phosphorous acid, react with its "activated" form prepared "in situ" from phosphorous(III) chloride and acetic acid to give the desired 1-amidoalkylphosphonic acids 2 in high yield.
