52054-83-8

Upstream product

• 59574-65-1 2-(3-butenyloxy)tetrahydropyran 
• 7022-45-9 2-(methylsulfanyl)benzaldehyde 
• 100-52-7 benzaldehyde 
• 58766-02-2 4-<(tetrahydropyran-2-yl)oxy>butylmagnesium chloride 
• 52103-12-5 3-iodopropyl tetrahydro-2H-pyran-2-yl ether 
• 17851-98-8 1-phenyl-1-(tributylstannyloxy)ethene 
• 769121-67-7 1-Phenyl-5-(tetrahydro-pyran-2-yloxy)-pentan-1-ol 
• 42330-88-1 1-chloro-3-(2-tetrahydropyranyloxy)propane 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 1011-62-7 5-hydroxy-1-phenylpentan-1-one 
• 98078-09-2 N'-(5-hydroxy-1-phenylpentylidene)-4-methylbenzenesulfonohydrazide 
• 98078-13-8 5-phenyl-4-pentenyl tetrahydropyranyl ether 
• 13159-16-5 5-phenyl-4-penten-1-ol 
• 825-54-7 cyclopent-1-en-1-ylbenzene 
• 98078-10-5 C₂₃H₃₀N₂O₄S 

Relevant academic research and scientific papers

Traceless chelation-controlled rhodium-catalyzed intermolecular alkene and alkyne hydroacylation

A new functional-group tolerant, rhodium-catalyzed, sulfide-reduction process is combined with rhodium-catalyzed chelation-controlled hydroacylation reactions to give a traceless hydroacylation protocol. Aryl- and alkenyl aldehydes can be combined with both alkenes, alkynes and allenes to give traceless products in high yields. A preliminary mechanistic proposal is also presented. Traceless catalysis: The powerful combination of a chelation-controlled hydroacylation process and a new rhodium-catalyzed sulfide reduction gave the products of traceless hydroacylation. Aryl- and alkenyl aldehydes can be combined with alkenes, alkynes, and allenes to deliver traceless products in high yields (see scheme). Copyright

Synthetic utility of stannyl enolates as radical alkylating agents

(Equation presented) The radical-initiated β-ketoalkylation of haloalkanes with tributylstannyl enolates is described. Stannyl enolates derived from aromatic ketones are reactive toward the homolytic β-ketoalkylation of simple haloalkanes as well as those activated by an electron-withdrawing group. The reactivity of stannyl enolates as radical alkylating agents can be utilized for an efficient three-component coupling reaction among stannyl enolates, haloalkanes, and electron-deficient alkenes.

A NOVEL CYCLIZATION REACTION OF OXIDO DIAZOALKANES: FORMATION OF 1-SUBSTITUTED CYCLOALKENES

The thermal decomposition of dialkali metal salts of δ-hydroxybutyl ketone and ε-hydroxypentyl ketone tosylhydrazones in diglyme at 80-120 deg C produced the 1-substituted cyclopentene and cyclohexene, respectively.