52084-13-6

Basic information

• Product Name: H-VAL-PNA
• Synonyms: L-VAL-PARANITROANILIDE;L-VAL-PNA;L-VALINE 4-NITROANILIDE;L-VALINE-P-NITROANALIDE;H-VAL-PNA;VALINE-PNA;L-VALINE P-NITROANILIDE);(2S)-2-Amino-3-methyl-N-(4-nitrophenyl)butanamide
• CAS NO: 52084-13-6
• Molecular Formula: C₁₁H₁₅N₃O₃
• Molecular Weight: 237.26
• Product Categories: Amino Acids
• Mol File: 52084-13-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 446.5 °C at 760 mmHg
• Flash Point: 223.8 °C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 3.63E-08mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: -15°C
• PKA: 12.84±0.70(Predicted)
• CAS DataBase Reference: H-VAL-PNA(CAS DataBase Reference)
• NIST Chemistry Reference: H-VAL-PNA(52084-13-6)
• EPA Substance Registry System: H-VAL-PNA(52084-13-6)

Safety Data

• Hazardous Substances Data: 52084-13-6(Hazardous Substances Data)

Usage

General Description

H-VAL-PNA, also known as Valine Peptide Nucleic Acid, is a type of Peptide Nucleic Acid (PNA), which are synthetic molecules used in molecular biology and genetic research. This chemical has a structure that mimics DNA and RNA, allowing it to bind tightly and specifically to these nucleic acids. This can be useful in various applications such as diagnostics, therapeutics, and molecular biology research. The "H-VAL" refers to the specific amino acid (valine) which is attached to the PNA, which can alter its properties and enhance its function. As a cutting-edge tool in genetics, H-VAL-PNA has the potential to contribute significantly to the advancements in the understanding of genetic diseases and their treatment.

InChI:InChI=1/C11H15N3O3/c1-7(2)10(12)11(15)13-8-3-5-9(6-4-8)14(16)17/h3-7,10H,12H2,1-2H3,(H,13,15)/t10-/m0/s1

Upstream product

• 61043-47-8 N-succinyl-Ala-Ala-Val-p-nitroanilide 
• 100-01-6 4-nitro-aniline 
• 13734-41-3 t-Boc-L-valine 
• 90105-48-9 (S)-1-[(S)-2-((S)-2-Amino-propionylamino)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-2-methyl-1-(4-nitro-phenylcarbamoyl)-propyl]-amide 
• 75670-93-8 Z-L-Val-pNA 

Downstream Products

• 77835-50-8 Boc-Pro-Val-pNA 
• 89545-66-4 Boc-D-Ala-Val-pNA 
• 187884-16-8 Boc-Leu-Pro-pNA 
• 89545-68-6 Boc-Leu-Pro-D-Ala-Val-pNA 
• 89545-63-1 Boc-Leu-Pro-Asn-Val-pNA 
• 61043-29-6 Z-Ala-Ala-Val-Nan 
• 100-01-6 4-nitro-aniline 
• 76402-50-1 H-D-Leu-L-Val-pNA 
• 87242-74-8 Boc-Leu-Ala-Sar-Val-pNA 
• 87251-38-5 Boc-Leu-D-Ala-Sar-Val-pNA 
• 87251-44-3 Boc-Leu-Ala-Gly-Val-pNA 
• 87251-37-4 Boc-Leu-D-Ala-Gly-Val-pNA 

Relevant articles and documents

L-valine dipeptide organocatalysts with two amide units for the direct asymmetric aldol reaction in brine

A series of valine dipeptide organocatalysts containing a primary amine group and two amide units have been developed and evaluated in the direct asymmetric intermolecular aldol reaction of 4-nitrobenzaldehyde and cyclohexanone. When 2,4-dinitrophenol (DN

Amino acids and peptides. XX. Inhibition of papain by succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide, a common sequence of endogenous thiol proteinase inhibitors.

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