52093-72-8Relevant academic research and scientific papers
Antibacterial and antitubercular activities of some diphenyl hydrazones and semicarbazones
Raja,Agarwal,Mahajan,Pandeya,Ananthan
scheme or table, p. 1384 - 1388 (2011/01/13)
Condensation of phenoxy or 4-bromophenoxy acetic acid hydrazide and substituted aryl semicarbazides with appropriate carbonyl compounds yield corresponding hydrazones and semicarbazones, respectively. The chemical structure of the synthesized compounds has been confirmed by UV, IR and 'H NMR spectral data. All the compounds have been investigated for their antibacterial activity against ten pathogenic strains and antitubercular activity against Mycobacterium tuberculosis H37 Rv. Compound 4f, Acetic acid, phenoxy-,[l-(4-chlorophenyl) ethylidene] hydrazide has been found to exhibit 80% inhibition in the preliminary antitubercular screening (MIC >6.25 |ig/mL).
An expedient method for the synthesis of acylhydrazones under microwave irradiation in solvent-free medium
Li, Jian-Ping,Zheng, Peng-Zhi,Zhu, Jun-Ge,Liu, Rui-Jie,Qu, Gui-Rong
, p. 90 - 92 (2007/10/03)
A simple, efficient and eco-friendly method for the synthesis of acylhydrazones from acylhydrazides and aldehydes under microwave (MW) irradiation was reported, no solvent and catalyst was used. The method is combined with a combinatorial approach and fou
Microwave assisted synthesis of new fungicidal pyrazoles
Kidwai,Bhushan,Misra
, p. 458 - 461 (2007/10/03)
Aromatic aldehydes are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized to give new pyrazoles under microwave irradiation and conventional heating using formic acid. The reaction rate is enhanced about 250 times by
