52095-57-5 Usage
Uses
Used in Pharmaceutical Research:
(Phenyl-2-pyridylmethyl)amine dihydrochloride is used as a building block in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic benefits.
Used in Antihistamine Development:
(Phenyl-2-pyridylmethyl)amine dihydrochloride is used as a potential antihistamine, helping to alleviate symptoms caused by histamine release, such as allergies and inflammatory conditions.
Used in Diabetes Treatment:
(Phenyl-2-pyridylmethyl)amine dihydrochloride is studied for its potential use in treating diabetes, as it may help regulate blood sugar levels and improve insulin sensitivity.
Used in Parkinson's Disease Treatment:
(Phenyl-2-pyridylmethyl)amine dihydrochloride is being investigated for its potential as a treatment for Parkinson's disease, as it may help alleviate symptoms and slow the progression of the condition.
Used in Organic Synthesis:
(Phenyl-2-pyridylmethyl)amine dihydrochloride is used as a versatile reagent in organic synthesis, enabling the creation of a wide range of chemical compounds for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 52095-57-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,9 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52095-57:
(7*5)+(6*2)+(5*0)+(4*9)+(3*5)+(2*5)+(1*7)=115
115 % 10 = 5
So 52095-57-5 is a valid CAS Registry Number.
52095-57-5Relevant academic research and scientific papers
Carbon-carbon bond formations at the benzylic positions of N-benzylxanthone imines and N-benzyldi-1-naphthyl ketone imine
Niwa, Takashi,Suehiro, Takafumi,Yorimitsu, Hideki,Oshima, Koichiro
experimental part, p. 5125 - 5131 (2009/11/30)
Two N-benzyl imines are designed to allow for carbon-carbon bond formations at the aminated benzylic positions. Direct benzylic arylation reactions of N-benzylxanthone imine with aryl chlorides proceed under palladium catalysis in the presence of cesium hydroxide, yielding the corresponding benzhydrylamine derivatives. Alkylation reactions of N-benzyldi-1-naphthyl ketone imine with alkyl halides in the presence of potassium tert-butoxide afford the corresponding 1-phenylalkylamines in high yields. Conjugate addition of N-benzyldi-1-naphthyl ketone imine is also described.
Palladium-catalyzed benzylic arylation of N-benzylxanthone imine
Niwa, Takashi,Yorimitsu, Hideki,Oshima, Koichiro
supporting information; experimental part, p. 4689 - 4691 (2009/05/13)
(Chemical Equation Presented) The direct benzylic arylation of N-benzylxanthone imine with aryl chloride proceeds under palladium catalysis, yielding the corresponding coupling product. The product is readily transformed to benzhydrylamine. Taking into consideration that the imine is readily available from benzylic amine, the overall transformation represents a formal cross-coupling reaction of aryl halide with α-aminobenzyl metal.
