52099-85-1Relevant academic research and scientific papers
N-cyanoamidine derivatives as anti-influenza agents
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, (2008/06/13)
Antiinfluenza A activity was found in compounds of the formula: STR1 wherein: X is 2-phenylethyl, 2-furanylmethyl, or STR2 where one of R1 and R2 is H and the other is phenylamino; Z is --SCH3 when X is STR3 when X is 2-ph
Structure-Activity Relations. Part 11. Biologically Active 2-Phenoxy-N-phenyl-3-pyridinecarboxamides: Potential Photoaffilnity Labels and Fused-ring Analogues
Bowden, Keith,Malik, Faisal P.,Pallett, Ken E.,Tomlinson, Ian D.
, p. 2901 - 2919 (2007/10/02)
Four substituted 2-phenoxy-N-phenyl-3-pyridinecarboxamides having azido or trifluoromethyldiazirinyl substituents have been prepared as potential photoaffinity labels for phytoene desaturase.Intramolecular hydrogen-bonding has been found to occur in 2-phenoxy-N-phenyl-3-pyridinecarboxamides.This finding and molecular graphic studies led to the design and synthesis of some substituted 1,3-diphenylpyridopyrimidine-2(1H),-4(3H)-diones and 1,3-diphenyl-2,3-dihydropyridopyrimidin-4(1H)-ones and a 4-hydroxy-1,3-diphenyl-1,8-naphthyridin-2(1H)-one.The biological activities of selected compounds towards Daucus carota have been measured.
