521067-39-0Relevant academic research and scientific papers
An Efficient Stereoselective Synthesis of Cytotoxic 8-Epipuupehedione
Armstrong, Veronica,Barrero, Alejandro F.,Alvarez-Manzaneda, Enrique J.,Cortes, Manuel,Sepulveda, Beatriz
, p. 1382 - 1383 (2007/10/03)
An efficient and highly stereoselective synthesis of cytotoxic 8-epipuupehedione (1b) was achieved starting from natural (-)-drimenol (6). The key step to obtain stereoselectivity was the simultaneous demethylation and oxidation of the dihydrobenzopyran methoxy derivatives 10a and 10b.
