2104695-66-9Relevant academic research and scientific papers
(3 + 2)-Annulation of p-Quinamine and Aryne: A Strategy to Construct the Multisubstituted Hydrocarbazoles
Xu, Dengyu,Zhao, Yulong,Song, Dengpeng,Zhong, Zhuliang,Feng, Shangbiao,Xie, Xingang,Wang, Xiaolei,She, Xuegong
supporting information, p. 3600 - 3603 (2017/07/15)
A strategy for the synthesis of multisubstituted hydrocarbazoles has been developed through (3 + 2)-annulation of p-quinamines and arynes. In this way, new analogs of hydrocarbazoles with quaternary carbon center can be synthesized in satisfactory yield under mild conditions. Furthermore, this (3 + 2)-annulation can be easily scaled-up, and the products can be modified through simple transformation.
A domino process for benzyne preparation: Dual activation of o-(trimethylsilyl)phenols by nonafluorobutanesulfonyl fluoride
Ikawa, Takashi,Nishiyama, Tsuyoshi,Nosaki, Toshifumi,Takagi, Akira,Akai, Shuji
, p. 1730 - 1733 (2011/06/16)
Benzynes were generated from o-(trimethylsilyl)phenols using nonafluorobutanesulfonyl fluoride (NfF) by a domino process, i.e., the nonaflation of the phenolic hydroxyl group of o-(trimethylsilyl)phenols by NfF followed by the attack of the produced fluoride ion on the trimethylsilyl group. The generated benzyne immediately underwent various reactions to give polysubstituted benzenes.
