52107-92-3

Upstream product

• 54811-50-6 2-iodo-6-methylbenzoic acid 
• 118-90-1 ortho-methylbenzoic acid 
• 4389-50-8 2-amino-6-methylbenzoic acid 
• 52107-89-8 2-Iod-6-methylbenzamid 
• 52107-69-4 2-iodo-6-methylbenzonitrile 
• 56043-01-7 2-amino-6-methylbenzonitrile 

Downstream Products

• 52107-74-1 6-Iod-2-methylbenzophenon 
• 103440-55-7 2-methyl-6-iodobenzoic acid methyl ester 
• 1379773-05-3 N-ethyl-2-iodo-6-methylbenzamide 
• 1379481-58-9 2-((4-fluorophenyl)ethynyl)-N-(4-methoxyphenyl)-6-methylbenzamide 
• 1379481-71-6 C₄₆H₃₄F₂N₂O₄ 
• 1379481-73-8 2-iodo-N-(4-methoxyphenyl)-6-methylbenzamide 
• 1381766-55-7 2-((2-(dimethylamino)phenyl)ethynyl)-N-(4-methoxyphenyl)-6-methylbenzamide 
• 1381766-57-9 2-((2-(dimethylamino)-3-methoxyphenyl)ethynyl)-N-(4-methoxyphenyl)-6-methylbenzamide 
• 1381766-41-1 C₂₄H₂₀N₂O₂ 
• 1381766-42-2 C₂₅H₂₂N₂O₃ 
• 1563227-96-2 9-(2'-iodo-6'-methylbenzoyl)-3-bromocarbazole 
• 1442110-94-2 1-(2-iodo-6-methylbenzoyl)-2-methyl-1H-indol 
• 861840-51-9 methyl 2-(bromomethyl)-6-iodobenzoate 

Relevant academic research and scientific papers

α-Oxocarboxylic Acids as Three-Carbon Insertion Units for Palladium-Catalyzed Decarboxylative Cascade Synthesis of Diverse Fused Heteropolycycles

A novel palladium-catalyzed decarboxylative cascade cyclization for the assembly of diverse fused heteropolycycles by employing α-oxocarboxylic acids as three-carbon insertion units is reported. This protocol enables the synthesis of isoquinolinedione- and indolo[2,1-a]isoquinolinone-fused benzocycloheptanones in moderate to good yields by the use of different aryl iodides, including alkene-tethered 2-iodobenzamides and 2-(2-iodophenyl)-1H-indoles. Notably, the approach achieves simultaneous construction of both six- and seven-membered rings via sequential intramolecular carbopalladation, C-H activation, and decarboxylation.

Heterocyclic compounds and uses thereof

Heterocyclic entities that modulate PI3 kinase activity, pharmaceutical compositions containing the isoquinolone entities, and methods of using these chemical entities for treating diseases and conditions associated with P13 kinase activity are described

Copper-catalyzed cross-coupling interrupted by an opportunistic smiles rearrangement: An efficient domino approach to dibenzoxazepinones

Unexpected Smiles! An unusual and highly regioselective synthesis of dibenzoxazepinones by a domino sequence assisted by an unexpected Smiles rearrangement is reported. The process is effective on electronically differentiated phenols and shows a high tolerance to variation in the benzamide substituents. A plausible path for the reaction, supported by preliminary mechanistic data, is offered. Copyright

Synergistic effect of palladium and copper catalysts: Catalytic cyclizative dimerization of ortho-(1-alkynyl)benzamides leading to axially chiral 1,3-butadienes

Two is better than one: In the presence of Pd(OAc)2 and Cu(OAc)2, o-(1-alkynyl)benzamides 1 were converted into bis-iminobenzoisofurans with an axially chiral 1,3-diene 2 unit. The coexistence of both Pd and Cu catalysts was found to be essential for both the cyclizative dimerization process and for the observed unusual cyclization mode. Copyright

Palladium(II)-catalyzed intramolecular diamination of alkynes under aerobic oxidative conditions: Catalytic turnover of an iodide ion

"I" did it: A sequential intramolecular amination/N- demethylation/amidation of internal acetylenes in the presence of a catalytic amount of Pd(OAc)2 and nBu4NI afforded indolo[3,2-c]isoquinolinones under mild aerobic conditions (see

Synthesis of 2-substituted β-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon

β-Cyclodextrin was substituted by an iodosobenzoic acid derivative to create a catalytic hydrolytic activity against neurotoxic organophosphorus agents. The catalytic moiety was introduced on a secondary hydroxy group at the position 2 of a glucose unit.