521272-68-4Relevant academic research and scientific papers
Synthesis and characterisation of a suite of four chiral pyridyl alcohols derived from (-)-menthol
Cunningham, Desmond,Gallagher, Eva T.,Grayson, David H.,McArdle, Patrick J.,Storey, Christina B.,Wilcock, Deborah J.
, p. 2692 - 2698 (2007/10/03)
Reaction of menthylmagnesium chloride with pyridine-2-carbaldehyde gives a mixture of four isomeric chiral menthyl- and neomenthyl-substituted pyridylcarbinols which were fully characterised by a combination of spectroscopic and X-ray crystallographic methods. All of these alcohols catalyse the addition of diethylzinc to benzaldehyde, but with disappointing enantioselectivities.
