52128-56-0

Basic information

• Product Name: 3-(acetyloxy)-1,2,3-benzotriazin-4(3H)-one
• CAS NO: 52128-56-0
• Molecular Formula: C₉H₇N₃O₃
• Molecular Weight: 205.1702
• Mol File: 52128-56-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 327.1°C at 760 mmHg
• Flash Point: 151.6°C
• Density: 1.45g/cm³
• Vapor Pressure: 0.000206mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 3-(acetyloxy)-1,2,3-benzotriazin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(acetyloxy)-1,2,3-benzotriazin-4(3H)-one(52128-56-0)
• EPA Substance Registry System: 3-(acetyloxy)-1,2,3-benzotriazin-4(3H)-one(52128-56-0)

Safety Data

• Hazardous Substances Data: 52128-56-0(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 28230-32-2 3-hydroxy-3,4-dihydrobenzotriazine-4-one 

Relevant articles and documents

3-HYDROXY-4-OXO-1,2,3-TRIAZINES AND DERIVATIVES THEREOF FOR AMIDE AND ESTER BOND FORMATION

The present invention relates to the use of a compound of formula I as a coupling reagent in forming amide or ester bonds from a reaction between a carboxylic acid and an amine or an alcohol, respectively. The compounds of formula I are especially useful as coupling reagents in the preparation of peptide bonds during peptide synthesis. In particular, the compounds of formula I are useful in promoting the formation of reactive reaction intermediates, inhibiting side reactions and in suppression of racemization. In addition, the present invention provides novel compounds of Formula I, and salts of N-oxides thereof.