521294-03-1

Basic information

• Product Name: Benzeneacetic acid, 1,6-hexanediyl ester
• CAS NO: 521294-03-1
• Molecular Formula: C22H26O4
• Molecular Weight: 354.446
• Mol File: 521294-03-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 1,6-hexanediyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 1,6-hexanediyl ester(521294-03-1)
• EPA Substance Registry System: Benzeneacetic acid, 1,6-hexanediyl ester(521294-03-1)

Safety Data

• Hazardous Substances Data: 521294-03-1(Hazardous Substances Data)

Upstream product

• 629-11-8 1,6-hexanediol 
• 140-29-4 phenylacetonitrile 
• 63734-12-3 methyl 6-O-(tert-butyldimethylsilyl)-α-D-glucopyranoside 
• 101-41-7 benzeneacetic acid methyl ester 
• 103-82-2 phenylacetic acid 
• 599-67-7 1,1-diphenylethanol 
• 528-75-6 2,4-dinitrobenzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 880348-58-3 2-phenyl-acrylic acid 6-(2-phenyl-acryloyloxy)-hexyl Ester 

Relevant articles and documents

ZWITTERIONIC CATALYSTS FOR (TRANS)ESTERIFICATION: APPLICATION IN FLUOROINDOLE-DERIVATIVES AND BIODIESEL SYNTHESIS

An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

Four acid-catalysed dehydration reactions proceed without interference

Four acid-catalysed dehydration reactions can proceed in one pot, simultaneously and without interference, to yield one imine, one acetal (or boronic ester), one ester and one alkene, even though many other cross-products could be conceived. This advanced

Efficient and controllably selective preparation of esters using uronium-based coupling agents

Carboxylic acid esters can be prepared in excellent yields at room temperature from an acid and either a phenol or an aliphatic alcohol using the peptide coupling reagents, TBTU, TATU, or COMU, in the presence of organic bases. Reactions using TBTU and TATU are faster but do not occur with tertiary alcohols. Selectivity between reaction with primary or secondary alcohols in diols and polyols can be achieved with choice of base and coupling agent.