52145-93-4Relevant academic research and scientific papers
Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors
Reyes-Ramírez, Adelfo,Leyte-Lugo, Martha,Figueroa, Mario,Serrano-Alba, Trinidad,González-Andrade, Martín,Mata, Rachel
, p. 2699 - 2708 (2011/07/08)
Several analogs of gigantol (1) were synthesized to evaluate their effect on the complexes Ca2+-calmodulin (CaM) and Ca2+-CaM-CaM sensitive phosphodiesterase 1 (PDE1). The compounds belong to four structural groups including, 1,2-dip
SYNTHESIS OF ATR AND LIGHT SENSITIVE CIS-PHENOLIC CYCLOPROPANE DERIVATIVES
Afzal, Jalees,Magarian, Robert A.,Griffin, May,Pento, J. Thomas
, p. 3061 - 3068 (2007/10/02)
The synthesis of several cis-phenolic cyclopropanes, 6, 7, 8 and 13 is described.These cyclopropanes are new potential antiestrogens.A hydrogenolysis study of precursors, 5b, 5c, 5d, 10, 11, and 12, and a novel method for the prevention of gem-dichlorocyclopropane ring-opening during hydrogenolysis are discussed.
