52164-35-9

Basic information

• Product Name: (2-iodo-3-methylphenyl)(phenyl)methanone
• Synonyms: (2-iodo-3-methylphenyl)(phenyl)methanone
• CAS NO: 52164-35-9
• Molecular Weight: 322.145
• Mol File: 52164-35-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-iodo-3-methylphenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-iodo-3-methylphenyl)(phenyl)methanone(52164-35-9)
• EPA Substance Registry System: (2-iodo-3-methylphenyl)(phenyl)methanone(52164-35-9)

Safety Data

• Hazardous Substances Data: 52164-35-9(Hazardous Substances Data)

Upstream product

• 4389-45-1 3-methylantranilic acid 
• 108-86-1 bromobenzene 
• 5054-32-0 (2-amino-3-methylphenyl)(phenyl)methanone 
• 69797-49-5 2-amino-3-methylbenzonitrile 

Relevant articles and documents

Lewis or Br?nsted acid-catalysed reaction of propargylic alcohol-tethered alkylidenecyclopropanes with indoles and pyrroles for the preparation of polycyclic compounds tethered with indole or pyrrole motif

We developed a facile synthetic method to access cyclopenta[b]naphthalene derivatives via the Lewis or Br?nsted acid catalysed cascade nucleophilic addition, electronic cyclization, ring-opening rearrangement of propargylic alcohol-tethered alkylidenecyclopropanes with indole and pyrrole derivatives. The reaction exhibited a broad substrate scope and good functional group tolerance under metal-free conditions, affording the desired products in moderate to good yields.

Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-spirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution

A synthetic method for the construction of diiodinated all-carbon spirobiindene derivatives has been developed from the reaction of propargyl alcohol-tethered alkylidenecyclopropanes with iodine. The reaction proceeded through an iodination-initiated cascade intramolecular enyne cyclization and electrophilic aromatic substitution reaction process in 1,2-dichloroethane upon heating, giving desired spirocyclic products in moderate to excellent yields. Further transformation of the obtained products has also been presented.