52185-71-4

Basic information

• Product Name: 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol
• Synonyms: 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol;1-Benzyl-2,2,6,6-tetramethyl-4-hydroxypiperidine;4-Piperidinol, 2,2,6,6-tetramethyl-1-(phenylmethyl)-;Einecs 257-718-4
• CAS NO: 52185-71-4
• Molecular Formula: C₁₆H₂₅NO
• Molecular Weight: 247.3758
• EINECS: 257-718-4
• Mol File: 52185-71-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 341.9°Cat760mmHg
• Flash Point: 39.9°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 3E-05mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol(52185-71-4)
• EPA Substance Registry System: 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol(52185-71-4)

Safety Data

• Hazardous Substances Data: 52185-71-4(Hazardous Substances Data)

Usage

Chemical class

Piperidines

Explanation

1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol belongs to the class of piperidines, which are nitrogen-containing heterocyclic compounds.

Explanation

This compound has three alkyl groups attached to the nitrogen atom, making it a tertiary amine.

Explanation

1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol is derived from piperidinol, a known antioxidant and stabilizing agent.

Explanation

The compound exhibits antioxidant properties, which help in reducing oxidative stress in materials it is added to.

Explanation

1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol has stabilizing properties that enhance the resistance of materials to degradation.

Explanation

The compound is commonly used as a HALS in plastics, coatings, and other polymer materials, providing protection against UV radiation and preventing degradation caused by exposure to light.

Explanation

The specific molecular structure of 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol makes it an effective stabilizer for a wide range of applications.

Explanation

The compound is used in various applications, including plastics, coatings, and other polymer materials, to enhance their resistance to UV radiation and improve their durability.

Explanation

By providing effective stabilization against UV radiation and degradation, 1-benzyl-2,2,6,6-tetramethylpiperidin-4-ol contributes to the longevity and durability of various products and materials.

Type of amine

Tertiary amine

Derivative

Piperidinol derivative

Antioxidant properties

Reduces oxidative stress

Stabilizing properties

Enhances resistance to degradation

Hindered amine light stabilizer (HALS)

Protects against UV radiation

Molecular structure

Effective stabilizer

Applications

Plastics, coatings, and polymer materials

Contribution to longevity and durability

Prolongs the life of products and materials

InChI:InChI=1/C16H25NO/c1-15(2)10-14(18)11-16(3,4)17(15)12-13-8-6-5-7-9-13/h5-9,14,18H,10-12H2,1-4H3

Upstream product

• 2403-88-5 4-hydroxy-2,2,6,6-tetramethylpiperidine 
• 100-39-0 benzyl bromide 
• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 

Downstream Products

• 504-20-1 phorone 
• 100-46-9 benzylamine 
• 52981-86-9 N-benzyl-2,2,6,6-tetramethyl-piperidin-4-one 
• 76245-94-8 1-benzyl-2,2,6,6-tetramethyl-4-piperidyl vinyl ether 
• 89162-27-6 1-benzyl-4-(2,3-epoxypropoxy)-2,2,6,6-tetramethylpiperidine 

Relevant articles and documents

General methodology for the chemoselective N-alkylation of (2,2,6,6)-tetramethylpiperidin-4-ol: Contribution of microwave irradiation

A convenient method to access a broad variety of N-alkyl-(2,2,6,6)-tetramethylpiperidin-4-ol compounds is reported. The thermal treatment of a mixture of (2,2,6,6)-tetramethylpiperidin-4-ol and allyl or benzyl bromide derivatives gave the corresponding N–alkylated compounds in good yields while leaving the hydroxyl functional group intact. Whereas 40 h were needed to reach complete conversion, microwave irradiation allowed the reaction time to be reduced (20 min) and improved the yields in most cases.

COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM

Compounds of the formula I, and liquid-crystalline media, preferably having a nematic phase and negative dielectric anisotropy, comprising a) one or more compounds of the formula I and one or more compounds selected from b) one or more compounds of formula II and/or c) one or more compounds selected from compounds of formulae III-1 to III-4 and formula B Methods for making and using these liquid-crystalline media in electro-optical displays, particularly in active-matrix displays based on the VA, ECB, PALC, FFS or IPS effect and the displays which contain these media. Methods for stabilizing liquid-crystalline media with compounds of formula I, where the liquid-crystalline media comprise one or more compounds of the formula II and one or more compounds selected from compounds of the formulae III-1 to III-4 and formula B.