52186-16-0

Basic information

• Product Name: 3,5-dimethyl-2,6-diphenyltetrahydro-4H-pyran-4-one
• CAS NO: 52186-16-0
• Molecular Formula: C₁₉H₂₀O₂
• Molecular Weight: 280.3609
• Mol File: 52186-16-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 424.6°C at 760 mmHg
• Flash Point: 182.7°C
• Density: 1.068g/cm³
• Vapor Pressure: 2.05E-07mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 3,5-dimethyl-2,6-diphenyltetrahydro-4H-pyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethyl-2,6-diphenyltetrahydro-4H-pyran-4-one(52186-16-0)
• EPA Substance Registry System: 3,5-dimethyl-2,6-diphenyltetrahydro-4H-pyran-4-one(52186-16-0)

Safety Data

• Hazardous Substances Data: 52186-16-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 96-22-0 pentan-3-one 
• 67405-37-2 t-2,t-6-diphenyl-c-3,c-5-dimethyloxan-r-4-ol 
• 75391-07-0 2-methyl-1-phenylpent-1-en-3-one 

Downstream Products

• 41025-06-3 2,5-dimethyl-3,4-diphenyl-cyclopentanone 

Relevant articles and documents

Conformational effects upon the oxidation of some substituted oxan-4-ols

Kinetics of oxidation of some epimeric pairs of oxan-4-ols by pyridinium fluorochromate (PFC) in the presence of sulphuric acid in aqueous acetic acid at 60°C have been investigated. The rate of oxidation is first order with respect to both the oxidant and the substrate concentrations at constant [acid]. The effect of solvent polarity on the reaction rates has also been studied. The order with respect to [H3O+] is found to be fractional at constant ionic strength in sulphuric acid. A suitable mechanism and the corresponding rate equation have been proposed. The reactivities of oxan-4-ols are rationalized on the basis of their conformational features. A twist conformation is assigned to t-2,t-6-diphenyl-c-3,c-5-dimethyloxan-r-4-ol and c-2,c-6-diphenyl-t-3,t-5-dimethyloxan-r-4-ol based on their oxidation rate constants.