Cas 5219-89-6,3-Amino-4-phenyl-6-trifluoromethyl-1H-quinolin-2-one

5219-89-6

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Basic information

Product Name: 3-Amino-4-phenyl-6-trifluoromethyl-1H-quinolin-2-one
Synonyms:
CAS NO:5219-89-6
Molecular Formula:
Molecular Weight: 304.271
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-Amino-4-phenyl-6-trifluoromethyl-1H-quinolin-2-one(CAS DataBase Reference)
NIST Chemistry Reference: 3-Amino-4-phenyl-6-trifluoromethyl-1H-quinolin-2-one(5219-89-6)
EPA Substance Registry System: 3-Amino-4-phenyl-6-trifluoromethyl-1H-quinolin-2-one(5219-89-6)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 5219-89-6(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 5219-89-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,1 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5219-89:
(6*5)+(5*2)+(4*1)+(3*9)+(2*8)+(1*9)=96
96 % 10 = 6
So 5219-89-6 is a valid CAS Registry Number.

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5219-89-6Downstream Products

5219-89-6Relevant academic research and scientific papers

The synthesis and structure-activity relationships of 4-aryl-3-aminoquinolin-2-ones: A new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for post-stroke neuroprotection

Hewawasam, Piyasena,Fan, Wenhong,Knipe, Jay,Moon, Sandra L.,Boissard, Christopher G.,Gribkoff, Valentin K.,Starrett Jr., John E

, p. 1779 - 1783 (2007/10/03)

A series of 4-aryl-3-aminoquinoline-2-one derivatives was synthesized and evaluated as activators of the cloned maxi-K channel mSlo (hSlo) expressed in Xenopus laevis oocytes using electrophysiological methods. A brain penetrable activator of maxi-K channels was identified and shown to be significantly active in the MCAO model of stroke.

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