521969-46-0

Basic information

• Product Name: Methanone, phenyl[4-(phenylmethyl)-2-morpholinyl]-
• CAS NO: 521969-46-0
• Molecular Formula: C18H19NO2
• Molecular Weight: 281.354
• Mol File: 521969-46-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl[4-(phenylmethyl)-2-morpholinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl[4-(phenylmethyl)-2-morpholinyl]-(521969-46-0)
• EPA Substance Registry System: Methanone, phenyl[4-(phenylmethyl)-2-morpholinyl]-(521969-46-0)

Safety Data

• Hazardous Substances Data: 521969-46-0(Hazardous Substances Data)

Upstream product

• 104-63-2 N-Benzylethanolamine 
• 108-86-1 bromobenzene 
• 147767-51-9 4-benzyl-2-cyanomorpholine 
• 100-59-4 phenylmagnesium chloride 

Downstream Products

• 664361-10-8 (2S)-(4-benzyl-morpholin-2-yl)-phenyl-methanone 
• 664361-21-1 4-benzyl-2-(2-phenyl-oxiranyl)-morpholine 
• 800407-81-2 (S,R)-1-(4-benzyl-morpholin-2-yl)-1-phenyl-2-(2-trifluorometoxy-phenyl)-ethanol 
• 800407-79-8 (S,R)-1-(4-benzyl-morpholin-2-yl)-2-(2-isopropoxy-phenyl)-1-phenyl-ethanol 
• 800407-86-7 (S,R)-1-(4-benzyl-morpholin-2-yl)-2-(5-fluoro-2-methoxy-phenyl)-1-phenyl-ethanol 
• 800407-77-6 (S,R)-1-(4-benzyl-morpholin-2-yl)-2-(2-methoxy-phenyl)-1-phenyl-ethanol 
• 935762-23-5 4-benzyl-2-{2-[2-(tert-butyl-dimethyl-silanyloxy)-phenyl]-1-phenyl-ethylidene}-morpholine 
• 860013-78-1 Z-4-benzyl-2-[2-(2-phenoxy-phenyl)-1-phenyl-ethylidene]-morpholine 
• 860013-74-7 Z-4-benzyl-2-(2-biphenyl-2-yl-1-phenyl-ethylidene)-morpholine 

Relevant articles and documents

Synthesis and evaluation of fluorinated analogues of monoamine reuptake inhibitors

The synthesis of two series of fluorinated analogues of monoamines reuptake inhibitors based on tertiary alcohols 2-substituted morpholines scaffold has been achieved through the incorporation of fluorinated substituent into 2-substituted morpholino ketones. Their binding affinities have been measured on different monoamine transporters.

TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a learning disability or a Motor Skills Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION

Selective norepinephrine reuptake inhibitors are useful for the prevention or treatment of hot flashes, vasomotor symptoms, impulse control disorders or personality change due to a general medical condition.