52197-08-7

Usage

Type of compound

pyridine derivative

Contains

a methylsulfanyl group and an oxygen atom attached to the pyridine ring

Potential uses

in the pharmaceutical and agricultural industries, as it may have biological activity and could be used as a building block for the synthesis of other organic compounds

Possible applications

in research and development for its unique chemical properties

Additional information

further studies and research are needed to fully understand the potential uses and properties of 2-(methylsulfanyl)pyridine 1-oxide.

Upstream product

• 3811-73-2 2-mercaptopyridine-1-oxide sodium salt 
• 77-78-1 dimethyl sulfate 
• 1121-30-8 1-hydroxy-2(1H)-pyridinethione 
• 74-88-4 methyl iodide 

Downstream Products

• 75853-85-9 methyl 2-(N-oxy-pyridyl) sulfoxide 
• 76455-92-0 C₁₃H₁₄N₂O₃S₂ 

Relevant academic research and scientific papers

The Invention of New Radical Chain Reactions. Part 9. Further Radical Chemistry of Thiohydroxamic Esters; Formation of Carbon-Carbon Bonds

Carbon radicals derived from the esters of several types of thiohydroxamic acids have been trapped in a number of different ways.Particular attention has been paid to carbon-carbon bond formation by addition to suitably activated ethylenic linkages.Carboxylic acids can be conveniently converted into homo- and bishomo-acids by free radical chemistry based on thiohydroxamic esters.In a coda the tautomerism of the thiohydroxamic acids have been examined by physical methods.It is confirmed that the esters used are derivatives of the thione tautomer.

Syntheses and Some Properties of Sulfoxides, Sulfilimines, Aminosulfonium Salts and Sulfoximines Containing Pyridine Nuclei

Several 2-pyridyl sulfides (1) (e.g., methyl (1a), ethyl (1b), isopropyl (1c), benzyl (1d), 1-phenylethyl (1e), l-menthyl (1f) 2-pyridyl sulfides); and bis(2-pyridylthio)methane (1g), and methyl 2-(N-oxy-pyridyl) sulfide (1h) were prepared by the usual method.Sulfoxides (2) were prepared by oxidation of the corresponding sulfides with m-chloroperbenzoic acid in good yields.A few sulfoxides were found to work as phase-transfer catalysts for some typical nucleophilic reactions in nonpolar solvents such as benzene, and in two-phase systems such as benzene-water.S-2-Pyridyl-N-(p-toluenesulfonyl) sulfinilimines (3) were prepared upon treatment of sulfides with Chloramine-T.Hydrolysis of N-(p-toluenesulfonyl)-2-pyridyl-o-tolylsulfilimine (3i) with conc. sulfuric acid gave the corresponding free sulfilimine in a moderate yield.S-2-Pyridyl sulfoximines (4) were not obtained by the general method from the sulfoxides and hydrazoic acid.Alkyl-2-pyridyl sulfoximines, however, were obtained by oxidation of the free sulfilimines derived from the corresponding aminosulfonium salts (5) prepared by reaction of the sulfides with mesitylene-sulfonylhydroxylamine (MSH).These free sulfilimines and sulfoximines thus prepared were found to give adducts with a few copper salts.